Could a simple enema help kidney patients flush out toxins?

NCT ID NCT07394920

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether a sodium bicarbonate enema can help relieve constipation and reduce harmful waste products in people with chronic kidney disease (CKD). The researchers believe the gut can act as an extra filter to remove toxins that build up when kidneys fail. They plan to enroll 100 adults with moderate to advanced CKD who are not yet on dialysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sodium bicarbonate enema

What this could lead to

If it works, this could offer a simple, low-cost way to relieve constipation and reduce harmful toxins in people with chronic kidney disease.

What could go wrong

This is a small, early-stage study with no phase assigned. The enema may not significantly lower toxins or improve constipation, and it may cause discomfort or electrolyte issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.