Could a simple enema help kidney patients flush out toxins?
NCT ID NCT07394920
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether a sodium bicarbonate enema can help relieve constipation and reduce harmful waste products in people with chronic kidney disease (CKD). The researchers believe the gut can act as an extra filter to remove toxins that build up when kidneys fail. They plan to enroll 100 adults with moderate to advanced CKD who are not yet on dialysis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sodium bicarbonate enema
- What this could lead to
- If it works, this could offer a simple, low-cost way to relieve constipation and reduce harmful toxins in people with chronic kidney disease.
- What could go wrong
- This is a small, early-stage study with no phase assigned. The enema may not significantly lower toxins or improve constipation, and it may cause discomfort or electrolyte issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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