Could a common gut drug clear the way for life-saving endoscopy?

NCT ID NCT07749300

Not yet recruiting Disease control Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests whether giving trimebutine maleate before an urgent endoscopy can clear blood and clots from the stomach, giving doctors a better view of the bleeding source. About 100 adults with acute upper gastrointestinal bleeding will receive either the drug or a placebo before their procedure. The study measures how clearly the stomach lining can be seen and whether the bleeding source is more easily identified.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Trimebutine Maleate
What this could lead to: If effective, this could improve the accuracy and speed of emergency endoscopy for upper GI bleeding, potentially reducing the need for repeat procedures.
What could go wrong: This is a mid-stage trial with a modest number of participants, so results may not be definitive. The drug may not significantly improve visualization, and there is a small risk of side effects or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE UPPER GASTROINTESTINAL BLEEDING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Gastrointestinal Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE UPPER GASTROINTESTINAL BLEEDING GASTROINTESTINAL HEMORRHAGE UPPER GASTROINTESTINAL BLEEDING

More trials for these conditions

Other studies related to the condition(s) this trial covers.