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Can an antibiotic help doctors see better during emergency stomach bleeding scopes?

NCT ID NCT06077916

Symptom relief Sponsor: Clinical Hospital Colentina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving azithromycin through a vein before an emergency endoscopy helps clear the stomach of blood and food, making it easier for doctors to find and treat the bleeding source. 224 adults with acute upper GI bleeding were randomly assigned to receive either azithromycin or a placebo. The main goal was to see if the drug improves the quality of the endoscopic view and reduces the need for a second procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
azithromycin
What this could lead to
If it works, this could make emergency endoscopy faster and more effective for people with upper GI bleeding, potentially reducing the need for repeat procedures.
What could go wrong
This is a small, single-center completed trial with no phase designation. Azithromycin may not improve stomach cleansing enough to change practice, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

224 people

The number who actually took part.

Started

Oct 2023

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * acute upper GI bleeding (\<12 hours) Exclusion Criteria: * prokinetics \<12 hours * allergy to azithromycin * use of contraindicated drugs (due to interactions) * pregnancy * physician option

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Conditions

The condition(s) this trial relates to.

Gastrointestinal Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Upper gastrointestinal bleeding

Contacts and locations

Locations

  • Colentina Clinical Hospital

    Bucharest, Bucharest, 020125, Romania

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