Clip or coil? new study tests best way to stop stomach bleeding

NCT ID NCT04902248

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two procedures for people whose upper stomach bleeding continues after initial treatment. One uses an endoscope to place a special clip on the bleeding spot; the other uses X-ray guidance to inject tiny coils into the bleeding artery. The trial will enroll 236 adults and track whether bleeding stops, how much blood is needed, and hospital stay length.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
over-the-scope clip (OTSC) device
What this could lead to
If successful, this could show that using an endoscopic clip is as effective as embolization for stopping stubborn stomach bleeding, potentially offering a less invasive first option.
What could go wrong
This is a relatively small, early-stage comparison. The two methods may prove equally effective, or one may be clearly better. Bleeding can still recur, and both procedures carry risks like infection or injury.

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Conditions

The condition(s) this trial relates to.

Gastrointestinal Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing friendship Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-••••

  • Endoscopy Centre, Prince of Wales Hospital

    RECRUITING

    Hong Kong, N.T., Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Huaxi Hospital of Sichuan University

    RECRUITING

    Chengdu, Sichuan, China

    Contact

    Contact

  • King Chulalongkorn Memorial Hospital

    RECRUITING

    Bangkok, Bangkok, Thailand

    Contact

    Contact

  • the First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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