Chinese University Of Hong Kong

This study is testing a new approach for people with obesity and type 2 diabetes. It combines two procedures done through the mouth: one uses mild electric pulses to regenerate the lining of the upper intestine, and the other reduces stomach size by stitching it like a sleeve. Th…

This study tests whether doing wall squat exercises for 14 minutes, three times a week, can lower blood pressure and slow the buildup of plaque in arteries. Researchers will compare 100 people doing the squats with 100 people doing gentle stretching, all with high blood pressure.…

This pilot study tests a 3-month program that combines online education, music-paced brisk walking, group discussions, and phone follow-ups for 40 adults with both metabolic syndrome and chronic kidney disease. The goal is to see if the program can reduce waist circumference and …

This study tests whether a specially designed health behavior program can help people with metabolic syndrome and chronic kidney disease reduce their waist size and improve kidney function. Researchers will compare the program to usual care in 160 adults, measuring changes in wai…

This study tests whether a GLP-1 drug, already used for diabetes, can slow down small vessel disease in the brain—a major cause of stroke, dementia, and mobility issues. About 110 adults aged 55 to 80 with moderate-to-severe disease will receive the drug or a placebo. The goal is…

This pilot study tests whether adding fludrocortisone (a steroid pill) to standard hydrocortisone treatment helps people with septic shock. Only 32 critically ill adults will take part. The main goal is not to see if the combo works, but to check if a larger, more definitive tria…

This study tests whether giving children with peanut allergy small, increasing amounts of peanut protein (oral immunotherapy) can help them tolerate more peanut without a reaction. It compares this approach to the standard care of strictly avoiding peanuts. The goal is to see if …

This study looks at whether adding focused radiation to spots where cancer is growing can help people with advanced liver cancer whose first immunotherapy treatment has partly stopped working. About 30 adults with limited new growth will receive radiation to those spots while con…

This study tests whether eating small, increasing amounts of boiled cashew flour can help children with cashew allergy tolerate the nut without severe reactions. 75 children aged 2 to 17 will receive either boiled cashew flour or a placebo over time. The goal is to see if this ap…

This study tests a new drug called dorzagliatin in 44 adults with a rare, inherited form of diabetes (GCK-MODY). The drug works by activating a key enzyme to help the body better control blood sugar. Participants will receive both the drug and a placebo at different times to see …

This study tests a procedure called TIF (transoral incisionless fundoplication) for people with chronic acid reflux (GERD) who don't get relief from medication. It is done through the mouth, no cuts, and aims to rebuild the valve between the stomach and esophagus. The study will …

This study tests whether draining the gallbladder using a thin tube passed through the mouth (EUS-GBD) right away is better than starting with antibiotics alone for elderly or very sick patients with mild to moderate gallbladder infection who cannot have surgery. About 110 partic…

This study tests whether adding a collagen scaffold during surgery for a torn Achilles tendon helps people heal better and faster. 48 adults will be randomly assigned to get either standard surgery or surgery plus the scaffold. Their tendon function, strength, and healing will be…

This study tests whether a TNF inhibitor (adalimumab biosimilar) is better than methotrexate at preventing bone damage in people with early psoriatic arthritis. About 108 adults with active disease and symptoms for less than 2 years will be randomly assigned to one of the two dru…

This study tests a procedure called EUS-guided radiofrequency ablation (RFA) for solid tumors in the stomach, liver, kidney, or adrenal glands. It involves using an endoscope to insert a needle that heats and destroys tumor tissue. The study will enroll 30 adults who cannot have …

This study is testing a new robotic system called Medtronic Hugo™ for surgery on chest cancers. It will enroll 50 adults who need robotic surgery for tumors in the chest or lung. The goal is to see if the robot is safe and effective by measuring how often surgeons need to switch …

This study is testing a procedure called EUS-guided radiofrequency ablation (RFA) for people with pancreatic tumors who are not candidates for surgery. The procedure uses a thin needle passed through an endoscope to deliver heat directly to the tumor. Researchers want to see if i…

This study tests whether a medium-chain triglyceride (MCT) diet, given after lung resection surgery, can help people leave the hospital sooner. The diet bypasses the lymphatic system, potentially reducing fluid buildup and complications. Researchers will compare hospital stay len…

This study compares an oral medication called Vonoprazan to the standard high-dose IV proton pump inhibitor (PPI) for preventing rebleeding in people with bleeding peptic ulcers after endoscopic treatment. About 594 adults will be randomly assigned to receive either oral Vonopraz…

This study looks at whether people at moderate risk for heart problems should continue or stop taking aspirin before a colonoscopy. About 2,500 participants will be randomly assigned to take either aspirin or a placebo for a few days around the procedure. The goal is to see which…

This 5-year study tests whether dapagliflozin, a diabetes drug, can prevent serious liver complications in people with chronic hepatitis B and diabetes who already have early liver scarring. 412 participants will receive either dapagliflozin or a placebo daily. The goal is to see…

This study compares two procedures for people whose upper stomach bleeding continues after initial treatment. One uses an endoscope to place a special clip on the bleeding spot; the other uses X-ray guidance to inject tiny coils into the bleeding artery. The trial will enroll 236…

This study tests a newer, ultrasound-guided endoscopic technique to prevent repeat bleeding from enlarged veins in the stomach or esophagus of liver cancer patients. About 84 adults who recently had such bleeding controlled by standard endoscopy will be randomly assigned to recei…

This phase 2 trial is testing whether adding precise, high-dose radiation (SBRT) to standard immunotherapy drugs (atezolizumab plus bevacizumab) can help people with advanced liver cancer that has spread into the main portal vein. About 40 participants will receive the combinatio…

This study is for Chinese adults aged 18-50 with type 2 diabetes and obesity. It tests a 3-year program that combines medical treatment, counseling, an AI chatbot, and peer support to help with weight loss and improve physical and mental health. The goal is to see if this team-ba…

This study looks at whether giving clot-busting drugs to stroke patients who are already on blood thinners is safe and effective. About 260 adults who had a stroke while taking common blood thinners will be enrolled. The goal is to see if this treatment can improve recovery witho…

This study compares two endoscopic procedures—EFTR and STER—for removing small gastric GIST tumors (1.0–3.5 cm). About 136 adults from Hong Kong, mainland China, India, and Japan will be randomly assigned to one method. The goal is to see which technique achieves complete tumor r…

This study tests whether adding a local treatment (like radiation or ablation) to the standard drug osimertinib can better control advanced EGFR-mutated lung cancer. About 64 adults with stable disease after 3-6 months on osimertinib and up to 3 remaining active spots will be ran…

This study tests a new device called SpydrBlade Flex for a procedure that helps people with achalasia, a condition where the esophagus doesn't relax properly, making swallowing difficult. The device uses radiofrequency and microwave energy to cut muscle. Researchers will check if…

This study offers young female cancer patients the option to freeze a piece of their ovarian tissue before starting cancer treatment, then have it transplanted back later to restore fertility. The goal is to help preserve the chance of having biological children after cancer. Res…

This study offers young female cancer patients the chance to freeze a piece of their ovary before starting cancer treatment. After they recover, if their ovaries stop working, doctors can thaw and re-implant the tissue to try to restore fertility. The goal is to help these women …

This study tests whether rapidly adjusting cholesterol-lowering medications, based on frequent blood tests, helps heart disease patients reach their LDL cholesterol targets faster. Researchers will enroll 1000 adults with coronary artery disease and monitor their cholesterol leve…

This study tests a new robotic system with an extra arm for stomach cancer surgery. Ten adults with stomach cancer will have their surgery using this robot. The goal is to see if the robot is safe and can complete the surgery without switching to other methods.

This study tests if doing wall squats (a type of isometric exercise) can lower blood pressure better than stretching in people with hypertension. About 390 adults who are not very active will be randomly assigned to either a wall-squat or stretching program for 24 weeks, with fol…

This study tests whether a telemedicine system (HealthCap app) can keep blood pressure under control as well as regular face-to-face doctor visits in people with stable hypertension. About 364 participants will either use the app for remote monitoring and automatic medication ref…

This study tests whether thiazide diuretics (water pills) can lower blood pressure in people on peritoneal dialysis who have high blood pressure. About 40 adults with end-stage kidney disease will take the drug and have their blood pressure, weight, and body fluid levels measured…

This study tests a milder form of IVF called CAPA in-vitro oocyte maturation (IVM). Instead of giving women strong hormones to stimulate egg growth, eggs are collected early and matured in a lab. The goal is to reduce side effects and costs for women with infertility or those pre…

This study tests a mobile app program to help smokers with cancer quit. Participants can choose their own quit schedule and receive supportive text messages. The goal is to see if this personalized approach leads to more people quitting compared to standard advice. The study invo…

This study tests whether baricitinib, a JAK inhibitor, can heal bone erosion in people with active rheumatoid arthritis. Sixty adults with moderate-to-severe RA and at least one bone erosion will receive either baricitinib or a placebo for 24 weeks. The main goal is to see if the…

This study compares two surgical methods for repairing a torn aorta, a life-threatening emergency. Half of the 72 participants will receive standard surgery, and the other half will also get a special stent designed to reduce the risk of future tears and the need for more operati…

This study is testing whether measuring TB DNA in blood and urine can help diagnose tuberculosis and track treatment progress. Current TB tests can be slow or require invasive procedures. The trial will enroll 85 people with active TB, latent TB, or no TB to see how accurate the …

This study tests an AI tool called EndoAIM that helps doctors measure the size of polyps found during a colonoscopy. Accurate size measurement is important because larger polyps (over 10 mm) have a higher risk of becoming cancer. The study will enroll 278 adults undergoing colono…

This study tests a wireless capsule called Hemopill that patients swallow to detect active bleeding in the upper digestive tract. Researchers will compare its accuracy to standard endoscopy in 193 people with signs of bleeding. If it works, the capsule could help doctors quickly …

This study tests whether high-resolution MRI can find subtle brain lesions that cause focal epilepsy but are missed by standard scans. Researchers will scan 66 adults with drug-resistant epilepsy and compare results to surgical findings. If successful, this could improve diagnosi…

This study is testing a special 3D MRI technique called neurogram imaging to better see the tiny branches of the facial nerve inside the parotid gland before surgery for parotid tumors. The goal is to help surgeons avoid accidentally injuring these nerves during tumor removal, wh…

This study is testing a new laboratory method that looks for DNA fragments from tuberculosis bacteria in fluid around the lungs (pleural effusion). The goal is to see if this test can diagnose tuberculous pleurisy more accurately than current tests. Researchers will study 400 adu…

This study tests a new method using an endoscope with ultrasound to measure pressure in the liver's blood vessels. It aims to see if this technique is safe and can predict complications like bleeding in 30 patients with cirrhosis from chronic hepatitis. The procedure is done duri…

This study tests whether an artificial intelligence (AI) tool can diagnose aortic regurgitation—a leaky heart valve—more accurately than standard manual methods. About 540 adults with confirmed aortic regurgitation will be randomly assigned to either AI-assisted or traditional di…

This study is testing whether an artificial intelligence program can help detect lung cancer early in non-smokers aged 50 to 75 who have a close family member with lung cancer. About 3,000 participants will get a low-dose CT scan of their chest, and the AI will analyze the images…

This study tests a new, fast MRI technique that measures collagen in the liver to detect scarring (fibrosis) without a needle biopsy. Researchers will compare the MRI results with standard tests in 200 adults with liver disease and healthy volunteers. The goal is to find a safer,…

This study tests a new blood test called HerResolve™ to see if it can accurately detect endometriosis in women aged 18 to 49 who have symptoms like pelvic pain or abnormal bleeding. About 100 participants will give a blood sample before their scheduled laparoscopy (a surgical pro…

This study tests a new skin test (C-TST) to find hidden tuberculosis (TB) infection in people with rheumatic diseases like rheumatoid arthritis who are about to start powerful medications called biologics. These drugs can reactivate dormant TB, so accurate screening is critical. …

This study tests a digital sleep platform that offers different levels of help based on how severe a person's insomnia symptoms are. Over 1,000 adults in Hong Kong with mild sleep issues will take part. The goal is to see if this stepped-care approach can prevent full-blown insom…

This study tests whether giving emergency department visitors a health screening and personalized advice can help them adopt healthier lifestyles and prevent non-communicable diseases like heart disease and diabetes. Over 1,100 adults in Hong Kong who have at least one unhealthy …

This study tests a stepped care model for delivering cognitive behavioral therapy for insomnia (CBT-I) to 1100 adults across 18 districts in Hong Kong. Participants first receive online self-help CBT-I, and those who need more support get therapist-guided sessions. The goal is to…

This pilot study tests a mindfulness-based music breathing program for older adults (65+) with mild to moderate anxiety or depression. The goal is to see if it boosts resilience and eases symptoms like loneliness and worry. Forty participants will be randomly assigned to the prog…

This study tests a 12-week dance program designed for stroke survivors who have weakness on one side of the body. The program combines movement improvisation and adaptive dance to help improve balance, mobility, confidence, and participation in daily and social activities. Resear…

This study tests a 6-week virtual program called PVI that helps young stroke survivors build personal resources through inclusive volunteering. Researchers want to see if it improves work ability, self-confidence, and emotional well-being. 160 participants aged 18-64 who had a st…

This study tests a program that combines storytelling and practical skills training to help young adults (ages 18-64) who have had a stroke feel more connected and capable in their communities. Over six months, 208 participants will attend eight one-on-one sessions with a facilit…

This study tests whether a gentle electrical stimulation device (acu-TENS) can reduce pain during a procedure called manual vacuum aspiration, used to treat early pregnancy loss. About 108 women will be randomly assigned to receive real acu-TENS or a sham device. The goal is to s…

This study tests whether personalized health coaching can reduce chronic muscle and joint pain in people aged 60 and older. 268 participants will either receive four face-to-face coaching sessions focused on exercise, diet, stress, sleep, social support, and avoiding risky substa…

This study tests whether listening to music during a first-trimester abortion procedure can help reduce pain and anxiety. 176 women will be randomly assigned to either receive routine care plus music through headphones, or routine care alone. Researchers will measure pain and anx…

This study tests whether giving a nerve block early, rather than waiting, can better control pain in people with inoperable pancreatic cancer. The procedure uses an endoscope to inject numbing medication near nerves that carry pain signals. Researchers will compare pain scores an…

This study tests a new robotic system designed to help surgeons remove kidney stones. The robot controls the surgical tools and can even perform some steps on its own with AI guidance. The trial will include 15 adults with small kidney stones to see if the robot can complete the …

This study tests whether practicing nunchaku exercises can reduce pain and improve movement in middle-aged and older adults with frozen shoulder. Fifty participants will be split into two groups: one doing nunchaku exercises and the other doing standard shoulder stretches and str…

This pilot study tests whether a 12-week sitting Tai Chi program can improve cognitive function, arm movement, balance, and mood in chronic stroke survivors who have memory or thinking problems. About 176 participants (88 stroke survivors and 88 caregivers) will be randomly assig…

This study is testing whether a genetic test can help doctors choose the best anti-nausea drugs for Chinese women with early breast cancer undergoing chemotherapy. About 200 participants will either receive standard anti-nausea medication or a personalized regimen based on their …

This study compares High-Intensity Focused Ultrasound (HIFU), a non-invasive procedure using sound waves to destroy fibroids, to myomectomy, a surgical removal. About 112 women aged 18-50 with symptomatic fibroids will be randomly assigned to one treatment. Researchers will track…

This study tests an online self-help platform called JCTH+ for university students in Hong Kong who have moderate to severe anxiety or depression. About 1,684 students will either use the platform plus usual services or just usual services. The goal is to see if the platform impr…

This study tests whether pulsed electromagnetic field (PEMF) therapy can reduce pain and improve function in people with mid-portion Achilles tendinopathy. Two hundred adults with confirmed Achilles tendon thickening and pain will receive either active PEMF or a sham device, plus…

This study is testing whether online therapy programs can help people with moderate to severe anxiety or depression. 320 participants will be randomly assigned to guided online CBT, self-guided CBT, mindfulness, or a waitlist. The goal is to see which approach best improves menta…

This study tests a new type of stent designed to drain bile from the liver in patients whose bile ducts are blocked by cancer. The stent is placed using an endoscope guided by ultrasound, without major surgery. The goal is to see if the stent is safe and works well in 20 adults w…

This study tests whether a specific nerve block (intertransverse process block) can help adults recover better and have less pain after elective heart surgery. 96 participants will receive either the block or a placebo before surgery. Researchers will measure quality of recovery …

This study looks at whether whole-body vibration therapy can reduce knee pain in people who still have pain after ACL reconstruction surgery. About 50 adults aged 18 to 60 with ongoing kneecap pain will use a vibrating platform for 8 weeks. The goal is to see if this simple train…

This study tests whether an 8-week mindfulness course can improve mental well-being and teaching skills in 160 Chinese teachers. Participants will learn mindfulness techniques and researchers will measure changes in stress, anxiety, and classroom effectiveness. The goal is to see…

This study tests if bright light therapy can ease depression in teens (ages 12-19) who tend to stay up late. 90 participants will receive either bright light or a placebo light to see if symptoms improve. The goal is to find a simple, drug-free way to help teens feel better.

This study tests a Chinese-language online therapy for social anxiety disorder in Hong Kong adults. About 110 participants will receive either therapist-guided treatment, coach-guided self-help, or be placed on a waitlist. The goal is to see if the cheaper coach-led option works …

This study tests a new soft robotic glove designed to help people who have had a stroke regain movement in their wrist and hand. Sixty participants will use the glove in 20 training sessions, and their progress will be compared to those receiving standard therapy. The glove uses …

This study tests whether a lower dose (2.5 mg) of a clot-busting drug called tPA works as well as the standard dose (10 mg) for treating pleural infections, which cause fluid buildup around the lungs. The drug is given through a chest tube along with another enzyme to help drain …

This study tests a nurse-led program called Dreamcatchers to help children aged 6-12 with cancer sleep better. The program uses relaxation techniques like breathing exercises and muscle relaxation instead of sleep medications. About 68 children will take part to see if this appro…

This study tests whether a technique called acu-TENS, which uses mild electrical pulses on acupuncture points, can reduce pain and stress during transvaginal egg retrieval for IVF. 144 women will be randomly assigned to receive real acu-TENS or a sham version. The main goal is to…

This study tests whether a fun, group-based music training program can help underprivileged children aged 8-12 who are at risk for depression and anxiety. The program uses games to teach musical instruments, aiming to boost resilience and reduce emotional distress. Researchers wi…

This pilot study tests a new type of brace that uses MRI scans to guide real-time adjustments for teens with mild scoliosis. The brace has air-filled pads that can be inflated or deflated to apply the right amount of pressure. Researchers want to see if this approach can quickly …

This study compares two surgeries for macular holes, a common cause of vision loss. The standard method uses a gas bubble to help the hole close, but the new technique skips the bubble. Researchers want to see if the new method works just as well and makes recovery easier for pat…

This pilot study tests whether an internet-based program teaching dialectical behaviour therapy skills can help adult smokers in Hong Kong quit or reduce smoking while also improving their psychological distress. Sixty participants will be randomly assigned to either the online s…

This study tests a non-invasive device that sends low-energy pulses to the brain, aiming to improve thinking and behavior in people with early Alzheimer's. Forty adults aged 60-90 will receive either real or sham (fake) pulses over several weeks. Researchers will measure changes …

This pilot study tests a virtual reality (VR) therapy session guided by an AI-powered virtual therapist to help reduce depression symptoms. Sixty Chinese young adults with mild to severe depression will either receive the VR therapy or join a waitlist. The goal is to see if this …

This study tests a mobile app designed to help children aged 9 to 16 who have recently finished cancer treatment manage their symptoms. The app provides educational materials and real-time support, plus personalized help from a nurse. Researchers want to see if using the app for …

This pilot study is testing whether a daily synbiotic supplement called SCV09 can improve behavioral symptoms in people with Alzheimer's disease. The supplement contains probiotics, prebiotics, and vitamins thought to support the gut-brain connection. Thirty participants aged 60-…

This study follows 200 obese Chinese patients undergoing weight-loss surgery to understand how nonalcoholic fatty liver disease (NAFLD) progresses. Researchers will take liver biopsies during surgery and track health markers over time. The goal is to find better ways to predict a…

This study follows 420 adults with HIV whose virus is fully suppressed by medication. Researchers want to see if switching to a different HIV drug regimen causes hidden drug resistance to appear. They will compare people who switch drugs with those who stay on their current treat…

This study looks at how young adults (ages 18-45) understand and behave toward risks for non-communicable diseases like heart disease and diabetes. Researchers will survey 5,000 Cantonese-speaking participants about smoking, alcohol, diet, and exercise. The goal is to find gaps i…

This study tests whether a school-based program, where students organize mental health talks, workshops, and activities, can improve wellbeing and reduce depression, anxiety, and suicidal thoughts among 18,000 Hong Kong secondary school students. Over three years, 130 schools wil…

This study aims to find out which factors—like hormone levels, follicle growth, and sperm quality—are linked to pregnancy success in intrauterine insemination (IUI). Researchers will track 3000 couples undergoing IUI to build a predictive model. The goal is to help doctors and pa…

This study tests an 8-week online program that teaches stroke survivors how to start their own business. The goal is to help them find meaningful work and improve their confidence and life satisfaction. The program is for adults aged 18-65 who had a stroke and have been out of pa…

This study is for women undergoing frozen embryo transfer with hormone replacement therapy. It aims to see if higher progesterone levels on the day of transfer lead to higher pregnancy rates. Researchers will track 370 participants to better understand this link and improve ferti…

This study aims to discover new ways to treat stomach cancer that has spread to other parts of the body. Researchers will collect tumor tissue, blood, and fluid samples from 100 patients to analyze their genes and proteins. The goal is to identify better treatment targets and tes…

This study is a global registry that collects health information from 500 adults with severe asthma. The goal is to track how patients respond to treatments and understand the disease better. The data will help researchers develop improved care and therapies for severe asthma.

This international registry collects data from 200 stomach cancer patients who undergo robot-assisted minimally invasive gastrectomy (RAMIG). The goal is to understand surgical techniques, outcomes, and the learning curve for surgeons. By standardizing data collection across cont…

This study is testing a new MRI method called T1rho that can take detailed pictures of the brain without needing a dye injection. Researchers will scan 30 healthy adults to measure what normal brain tissue looks like with this technique. The goal is to create a baseline of health…

This study tests whether a new EUS-guided pressure measurement (EUS-PPGM) can predict how well varices respond to endoscopic banding in people with cirrhosis. Researchers will measure portal pressure in 160 patients and follow them for one year to see if higher pressure at 3 mont…

This study looks back at how biologic drugs are being used to treat severe asthma in Hong Kong. Researchers will review the medical records of 360 adults to see which biologics are prescribed, how well they control asthma, and any side effects. The goal is to understand current p…

This study tests a personalized approach for patients with advanced liver or colorectal cancers that no longer respond to standard treatments. Doctors take a small sample of the tumor, grow it in the lab as 3D 'organoids', and test different drugs on them to see which works best.…

This study looks at how genes are linked to different types and severities of asthma in Chinese patients. Researchers will collect genetic data from 2,000 people with asthma to find common gene variants. The goal is to better understand asthma in this population, which has been u…

This study follows 1,350 people in Hong Kong households to see how their protection against COVID-19 changes over time. Researchers will measure antibodies from both vaccination and past infection. The goal is to understand how household immunity evolves and how it affects the ri…

This study looks at how tiny organisms in the airways, like bacteria and viruses, relate to different types of asthma in adults. Researchers will collect samples from 140 adults with asthma to see if certain microbial patterns are linked to asthma severity and control. The goal i…

This study tracks 350 stroke patients across the Asia-Pacific to see how well a proven clot-removal procedure (endovascular thrombectomy) works in everyday hospitals, not just in controlled trials. Researchers will analyze patient outcomes, imaging, and even the removed clots to …

This study aims to create a standard method for developing guidelines on how herbs and drugs interact. Researchers will survey 40 experts, including Chinese medicine practitioners and doctors, to agree on key framework components. They will also interview participants to understa…

This study follows 500 adults in Hong Kong with severe asthma who are on high-dose treatments (step 4 or 5 of GINA guidelines). Researchers will track how well their asthma is controlled and how often they have flare-ups over two years. The goal is to gather local data to help do…

This study will analyze data from 100,000 COPD patients in Hong Kong to build computer models that predict who is likely to be readmitted to the hospital or die within a year. The goal is to help doctors identify high-risk patients early. No new treatments are being tested; inste…

This study collects blood, tissue, and other samples from up to 10,000 people to create a biobank for research. The goal is to help scientists study the causes of diseases like cancer, heart disease, and diabetes. Participants provide samples and basic health data, but no treatme…

This study looks at how pieces of tumor DNA circulating in the blood change in 15 liver cancer patients receiving a precise type of radiotherapy called SBRT. Researchers will take blood samples before, during, and up to 6 months after treatment to see if these DNA changes can hel…

This study will follow 1,000 adults in Hong Kong who have both type 2 diabetes and a common fatty liver condition called MASLD. Researchers will collect health data and blood samples over time to see how the liver disease progresses and to find early markers of serious liver scar…

This study uses advanced 3D-rotational angiography to track how fatty plaques in brain arteries change over one year in 140 people who have had a stroke or mini-stroke. Participants will have two scans 12 months apart while managing heart risk factors. The goal is to understand p…

This study aims to understand if COVID-19 vaccines have any impact on brain health in healthy people. Researchers will use MRI scans to look for changes in the brain's blood vessels and structure. The study will follow 500 adults from Hong Kong who have already had a baseline bra…

This study looks at fatty buildup in brain arteries that can break off and cause strokes. Researchers want to see if high-risk plaques look different from harmless ones. They will use special imaging to compare plaques in 140 people who have had a stroke with those who have not.

This long-term study is tracking 5,000 adults in Hong Kong who either have a brain disease (like stroke or dementia) or are at high risk due to family history or early signs. Researchers will collect medical records and questionnaires every 6 months to find what factors lead to b…

This study is building a biobank of blood, spinal fluid, and tissue samples from 500 Chinese adults, including stroke patients, their families, and healthy volunteers. Researchers will analyze the samples to find genetic markers linked to stroke and its complications. The goal is…

This study compares two advanced techniques used when doctors have trouble reaching the bile duct during a procedure called ERCP. About 188 adults with difficult bile duct access will be randomly assigned to either an endoscopic ultrasound-guided rendezvous technique or an early …

This study compares two ways to guide prostate biopsies using MRI: cognitive-guided (doctor mentally aligns images) and MRI-ultrasound fusion (computer overlays images). It aims to see which method finds more clinically significant prostate cancers. The trial will enroll 1,250 me…

This study tests a new AI system (AI-ENDO) that helps doctors perform a type of keyhole surgery called endoscopic submucosal dissection (ESD) for early-stage cancers in the food pipe, stomach, or bowel. The AI works in the background at first, then provides real-time guidance on …

This study is collecting genetic and drug sensitivity data from 300 children with leukemia to better understand why some cases relapse and how to target them more precisely. Researchers will analyze tumor DNA, gene activity, and test drugs on patient cells in the lab. The goal is…

This study follows 100 cancer patients aged 0-50 who used fertility preservation services to protect their ability to have children. Researchers will review medical records to see which methods led to successful pregnancies and what factors—like age or treatment type—influenced o…

This study looks at how much women in Hong Kong know about common gynecological problems like PCOS, endometriosis, miscarriage, and infertility. Researchers will compare patients and the general public to find gaps in knowledge and barriers to getting care. The goal is to use thi…

This study aims to create an AI system that predicts which type of rehabilitation—like standard therapy, electrical stimulation, robotic training, or acupuncture—will help each stroke survivor recover the most movement in their arm. Researchers will collect data from 400 stroke s…

This study is creating a registry of 800 adults aged 18–50 with type 2 diabetes and obesity (called diabesity) in Hong Kong. Participants will receive health checks at the start and again after 3 years, including eye, foot, blood, and urine tests. The goal is to track how their h…

This pilot study is testing whether a flexible camera (ureteroscope) can be used under local anesthesia to check for cancer recurrence in the upper urinary tract after kidney-sparing surgery. Ten adults who have had such surgery will undergo the procedure in an outpatient setting…