New endoscopic heat treatment could help pancreatic cancer patients avoid surgery

NCT ID NCT03218345

Recruiting now Disease control Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing a procedure called EUS-guided radiofrequency ablation (RFA) for people with pancreatic tumors who are not candidates for surgery. The procedure uses a thin needle passed through an endoscope to deliver heat directly to the tumor. Researchers want to see if it is safe and effective, and will monitor for side effects like pancreatitis or thermal injury. The trial plans to enroll 30 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiofrequency ablation (RFA) delivered via an endoscope
What this could lead to: If it works, this could offer a minimally invasive treatment option for pancreatic tumors in patients who cannot have surgery.
What could go wrong: This is a small, early-phase study with only 30 participants, so results may not apply to everyone. Risks include pancreatitis, pancreatic leak, and thermal injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pancreatic ductal adenocarcinoma pancreatic neoplasm pancreatic neuroendocrine tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC NEOPLASMS

Contacts and locations

Locations

Department of Surgery, Prince of Wales Hospital
RECRUITING

Hong Kong, Hong Kong

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