New endoscopic heat treatment could help pancreatic cancer patients avoid surgery

NCT ID NCT03218345

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing a procedure called EUS-guided radiofrequency ablation (RFA) for people with pancreatic tumors who are not candidates for surgery. The procedure uses a thin needle passed through an endoscope to deliver heat directly to the tumor. Researchers want to see if it is safe and effective, and will monitor for side effects like pancreatitis or thermal injury. The trial plans to enroll 30 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiofrequency ablation (RFA) delivered via an endoscope

What this could lead to

If it works, this could offer a minimally invasive treatment option for pancreatic tumors in patients who cannot have surgery.

What could go wrong

This is a small, early-phase study with only 30 participants, so results may not apply to everyone. Risks include pancreatitis, pancreatic leak, and thermal injury.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pancreatic ductal adenocarcinoma pancreatic neoplasm pancreatic neuroendocrine tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Surgery, Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••