New TB skin test could spare rheumatoid patients from hidden infection

NCT ID NCT06796647

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new skin test (C-TST) to find hidden tuberculosis (TB) infection in people with rheumatic diseases like rheumatoid arthritis who are about to start powerful medications called biologics. These drugs can reactivate dormant TB, so accurate screening is critical. Researchers will compare the new test with standard skin and blood tests in 100 adults, then follow them for two years to see who develops active TB.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ESAT6/CFP10 skin test (C-TST)

What this could lead to

If successful, this could provide a more accurate and convenient way to detect hidden TB infection in people with rheumatic diseases, helping prevent active TB when they start certain medications.

What could go wrong

This is a small, early-stage study with only 100 participants. The new test may not prove more accurate than existing methods, and results may not apply to all patient groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rheumatic disorder tuberculosis active tuberculosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • S.H. Ho Research Centre for Infectious Diseases

    RECRUITING

    Hong Kong, Hong Kong, 0000, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • S.H. Ho Research Centre for Infectious Diseases

    NOT_YET_RECRUITING

    Shatin, Hong Kong, 0000, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact