Electric pulses and stomach reshaping: a new hope for diabesity?

NCT ID NCT07660445

Recruiting now Disease control Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new approach for people with obesity and type 2 diabetes. It combines two procedures done through the mouth: one uses mild electric pulses to regenerate the lining of the upper intestine, and the other reduces stomach size by stitching it like a sleeve. The goal is to see if this combination helps with weight loss and blood sugar control. The trial is currently recruiting 20 participants in Hong Kong.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pulsed electric field (via pulsENDO catheter) and endoscopic sleeve gastroplasty
What this could lead to: If successful, this could offer a new, less invasive option to help people with obesity and type 2 diabetes better control their weight and blood sugar, potentially reducing their need for diabetes medications.
What could go wrong: This is a very small, early-stage trial with only 20 participants, so results may not apply to everyone. The procedures are new and carry risks like any endoscopic intervention, and it is not yet known if benefits will last long-term.

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Conditions

The condition(s) this trial relates to.

obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY TYPE 2 DIABETES MELLITUS

Contacts and locations

Locations

Prince of Wales Hospital, the Chinese University of Hong Kong
RECRUITING

Shatin, Hong Kong

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