Could a simple pill replace IV drips for bleeding ulcers?

NCT ID NCT05582174

First seen Mar 18, 2026 · Last updated May 16, 2026 · Updated 8 times

Summary

This study tests whether an oral medication called Vonoprazan works as well as the standard high-dose IV acid-reducing drugs to prevent rebleeding in people with bleeding stomach ulcers. About 594 adults who had an endoscopy to stop bleeding will be randomly assigned to one of the two treatments. The goal is to see if the pill can safely replace the IV drip, potentially simplifying care.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nanfang Hospital Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • Prince of Wales Hospital

    NOT_YET_RECRUITING

    Hong Kong, Hong Kong SAR, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shenzhen Pingshan District People's Hospital

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • The Second Affiliated Hospital The Chinese University of Hong Kong, Shenzhen & Longgang District People's Hospital of Shenzhen

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • The Second Affiliated Hospital of Guangzhou Medical University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • The Second Affiliated Hospital of Guangzhou University of Chinese Medicine

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • Yangjiang People's Hospital of Guangdong Medical University

    NOT_YET_RECRUITING

    Yangjiang, Guangdong, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

  • Zhuhai People's Hospital (Zhuhai Hospital Affiliated to Jinan University)

    NOT_YET_RECRUITING

    Zhuhai, Guangdong, China

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

Conditions

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