New study tests if draining the gallbladder early prevents repeat attacks in frail patients
NCT ID NCT05893511
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether draining the gallbladder using a thin tube passed through the mouth (EUS-GBD) right away is better than starting with antibiotics alone for elderly or very sick patients with mild to moderate gallbladder infection who cannot have surgery. About 110 participants will be randomly assigned to one of the two approaches. The main goal is to see if upfront drainage reduces the chance of another gallbladder infection within one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) procedure
- What this could lead to
- If successful, upfront drainage could become a standard treatment to prevent repeat gallbladder attacks in frail patients who cannot undergo surgery.
- What could go wrong
- This is a relatively small Phase 3 trial (110 patients), and the procedure carries risks like bleeding or infection. The benefit over antibiotics alone may not be large enough to change practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Chinese Universtiy of Hong Kong
RECRUITINGHong Kong, HONG KONG, 00000, Hong Kong
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Other studies related to the condition(s) this trial covers.
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