New study tests if draining the gallbladder early prevents repeat attacks in frail patients
NCT ID NCT05893511
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether draining the gallbladder using a thin tube passed through the mouth (EUS-GBD) right away is better than starting with antibiotics alone for elderly or very sick patients with mild to moderate gallbladder infection who cannot have surgery. About 110 participants will be randomly assigned to one of the two approaches. The main goal is to see if upfront drainage reduces the chance of another gallbladder infection within one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) procedure
What this could lead to
If successful, upfront drainage could become a standard treatment to prevent repeat gallbladder attacks in frail patients who cannot undergo surgery.
What could go wrong
This is a relatively small Phase 3 trial (110 patients), and the procedure carries risks like bleeding or infection. The benefit over antibiotics alone may not be large enough to change practice.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Chinese Universtiy of Hong Kong
RECRUITINGHong Kong, HONG KONG, 00000, Hong Kong
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••