Could a second steroid boost survival in septic shock? tiny trial paves way
NCT ID NCT07451886
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests whether adding fludrocortisone (a steroid pill) to standard hydrocortisone treatment helps people with septic shock. Only 32 critically ill adults will take part. The main goal is not to see if the combo works, but to check if a larger, more definitive trial is possible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fludrocortisone (a steroid hormone) given as a pill, plus standard hydrocortisone (another steroid) given intravenously
What this could lead to
If this pilot shows the larger trial is feasible, it could lead to a definitive study that may prove adding fludrocortisone saves more lives from septic shock.
What could go wrong
This is a very small pilot (32 patients) testing only whether a larger trial can be done, not whether the drug works. Even if the larger trial happens, the combination may not reduce deaths.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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North District Hospital
NOT_YET_RECRUITINGHong Kong, Hong Kong
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Pamela Youde Nethersole Hospital
NOT_YET_RECRUITINGHong Kong, Hong Kong
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Prince of Wales Hospital
RECRUITINGHong Kong, Hong Kong
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Princess Margaret Hospital
NOT_YET_RECRUITINGHong Kong, Hong Kong
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Queen Mary Hospital
NOT_YET_RECRUITINGHong Kong, Hong Kong