New tool could make achalasia surgery safer and more effective

NCT ID NCT07406945

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new device called SpydrBlade Flex for a procedure that helps people with achalasia, a condition where the esophagus doesn't relax properly, making swallowing difficult. The device uses radiofrequency and microwave energy to cut muscle. Researchers will check if the procedure works well and is safe in 73 adults. The goal is to improve swallowing and reduce complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SpydrBlade Flex device (radiofrequency and microwave ablation tool)

What this could lead to

If successful, this device could make the POEM procedure safer and more effective for treating achalasia, improving swallowing and quality of life.

What could go wrong

This is an early-stage study with only 73 participants. The device may not work better than existing tools, and risks like bleeding or infection remain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

achalasia Esophageal Achalasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Surgery, Faculty of Medicine, the Chinese University of Hong Kong

    RECRUITING

    Hong Kong, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • academy tertiary, IECED

    RECRUITING

    Guayaquil, Ecuador