Chinese University Of Hong Kong

This study is testing whether a telemedicine system can help people with well-controlled high blood pressure maintain their health as effectively as regular in-person doctor visits. Researchers will compare two groups of 364 participants over 12 months: one using an app for remot…

This small pilot study is testing whether a new probiotic formula (SCV09) can improve behavioral symptoms and daily functioning in people with Alzheimer's disease. Researchers are exploring the connection between gut health and brain function. The study will enroll 30 participant…

This study is testing whether adding focused radiation therapy can help control advanced liver cancer that has started to progress in a few spots while patients are on standard immunotherapy. Researchers want to see if zapping these specific progressing areas with radiation can h…

This study compares two surgical techniques for repairing macular holes, a condition that can cause permanent central vision loss. The standard surgery uses a gas bubble and requires patients to maintain a face-down position for days afterward. The new technique uses a different …

This study is testing a procedure that uses heat to destroy tumors in the stomach, liver, kidney, or adrenal glands. It is for patients who are not suitable candidates for surgery. Doctors guide a special needle using ultrasound to apply heat directly to the tumor. The main goal …

This study is testing whether a medication called baricitinib can help repair existing bone damage in people with active rheumatoid arthritis. Sixty adult patients with active arthritis and visible bone erosion will take either the real drug or a placebo pill daily for 24 weeks. …

This 5-year study is testing if a common diabetes medication, dapagliflozin, can prevent serious liver complications like cancer and liver failure in people who have both chronic hepatitis B and diabetes. About 412 participants will be randomly assigned to take either the real dr…

This study is testing if a lower dose of a medication (tPA) injected into the chest works as well as the standard dose for treating serious lung infections with fluid buildup. It aims to see if the lower dose can clear the infection effectively while possibly reducing the risk of…

This study is testing whether adding a special collagen patch during surgery helps people recover better from a torn Achilles tendon. 48 adults who need surgery will be randomly assigned to get the standard repair or the standard repair plus the patch. Researchers will compare ho…

This large study aims to settle a common medical dilemma: whether heart patients should continue or stop their daily aspirin before a colonoscopy. Researchers will compare two groups of over 2,500 patients to see which approach leads to fewer heart problems or serious bleeding ev…

This study compares two emergency treatments for severe stomach bleeding that continues after initial attempts to stop it. Researchers are testing whether special endoscopic clips placed during a scope procedure work as well as blocking the bleeding artery through a catheter. The…

This study is testing a new AI system designed to help surgeons during a minimally invasive procedure to remove early-stage cancers in the digestive tract. The AI provides real-time guidance, highlighting safe areas to cut and warning of risks like blood vessels, aiming to make t…

This small pilot study is testing a new type of brace for teenagers with mild to moderate scoliosis. The brace uses air pads that can be adjusted while the patient is inside an MRI scanner, allowing doctors to see and apply corrective pressure in real time. The goal is to see if …

This trial is for people with a specific type of advanced lung cancer (EGFR-mutated NSCLC) who have responded well to their first-line pill, osimertinib, but still have a few small, leftover cancer spots. It tests whether adding a targeted, high-dose radiation treatment (called l…

This study is testing if adding a common water pill (a thiazide diuretic) helps lower high blood pressure in people receiving peritoneal dialysis for kidney failure. It involves 40 patients who will take the pill for 90 days, then stop for a period, to compare the effects. The ma…

This study compares two advanced techniques doctors use when they have trouble accessing the bile duct during a common procedure called ERCP. When the standard method fails, doctors can either make a small cut (precut) or use ultrasound guidance to create a new path (rendezvous t…

This study is testing if adding a special stent during emergency surgery for a torn aorta (aortic dissection) leads to better long-term results. It will compare the standard surgery to the same surgery plus the stent implant in 72 patients. The main goal is to see if the stent re…

This study offers a fertility preservation option for young female cancer patients. It involves surgically removing and freezing a piece of ovarian tissue before cancer treatments like chemotherapy, which can damage fertility. The frozen tissue can later be transplanted back to p…

This study is testing a new, flexible medical tool designed to make a throat muscle procedure safer and more effective for people with achalasia, a condition that makes swallowing difficult. About 73 adult patients who need this specific procedure will have it performed with the …

This study aims to use artificial intelligence (AI) to create a personalized plan for stroke recovery. Researchers will gather detailed health data from 400 stroke survivors to train an AI system. The goal is for the AI to predict which type of rehabilitation therapy—like standar…

This study is testing a procedure that uses heat to destroy solid pancreatic tumors. It is for patients with pancreatic cancer or neuroendocrine tumors who are not suitable candidates for surgery. Doctors use an ultrasound-guided needle to apply radiofrequency energy to heat and …

This study is testing whether a digital platform called JCTH+ can help university students manage anxiety and depression better than the usual campus support services. Around 1,700 students in Hong Kong with moderate to severe symptoms will use the platform, which offers self-hel…

This study compares two common treatments for early psoriatic arthritis to see which one is better at preventing permanent joint damage. It will enroll 108 adults who have had symptoms for two years or less and have not yet tried these specific medications. Researchers will use d…

This study is testing if adding a precise, high-dose radiation treatment (SBRT) to a standard two-drug immunotherapy regimen can help people with advanced liver cancer that has spread into a major vein. The vein blockage makes the cancer much harder to treat and drastically short…

This study is testing a new, personalized approach to find effective treatments for patients with advanced liver or colorectal cancer that has stopped responding to standard therapies. Doctors will grow miniature 3D models of a patient's own tumor in the lab to test how it respon…

This study is testing if a simple wall squat exercise program can help lower high blood pressure in Chinese adults who don't get enough physical activity. 390 participants with high blood pressure will be randomly assigned to either do wall squats or stretching exercises for 24 w…

This study is testing a comprehensive 3-year care program for Chinese adults who have both diabetes and obesity (diabesity). The program uses a team of specialists, including a doctor, dietitian, and psychologist, along with technology like an AI chatbot and peer support. The mai…

This study is testing if a special diet containing medium-chain triglycerides (MCTs) can help patients recover faster after lung surgery. Researchers will give the MCT diet to some patients after their operation to see if it reduces fluid buildup and shortens their hospital stay …

This study is testing if a medication commonly used for diabetes (a GLP-1 analogue) can safely slow down or stop the progression of cerebral small vessel disease (cSVD), a major cause of stroke and dementia. It will involve 110 Chinese adults aged 55-80 who already have moderate …

This study is testing whether a personalized support program helps smokers who have cancer quit. About 1,450 participants in Hong Kong will either get brief advice to quit immediately or get to choose their own quit date and receive encouraging text messages for 6 months. The goa…

This study is testing if a newer, ultrasound-guided endoscopic procedure is better than standard treatment at preventing dangerous variceal re-bleeding in people with liver cancer (HCC). It will enroll 84 patients who have recently had a bleeding episode controlled. The main goal…

This study is testing if a new oral pill called Vonoprazan works as well as the current standard treatment—a high-dose intravenous (IV) drip—for preventing a stomach ulcer from bleeding again. It involves adults who have just had a bleeding ulcer successfully treated during a sco…

This study is testing whether a gentle, non-invasive brain stimulation treatment can help people with early Alzheimer's disease. The treatment, called Transcranial Pulse Stimulation (TPS), uses focused sound pulses aimed at the brain. Researchers will compare the real treatment t…

This study is testing a new robotic surgery system designed to help surgeons operate on stomach cancer. Ten patients in Hong Kong and Japan will have their cancer removed using this experimental robot with an extra 'fifth arm' for assistance. The main goal is to see if the proced…

This pilot study is testing an online therapy program designed to help people quit smoking while also managing feelings of stress, anxiety, or depression. The program teaches skills based on a therapy called Dialectical Behaviour Therapy. Researchers will recruit 60 adult smokers…

This study aims to find out if a common emergency stroke treatment (clot-busting drugs) is safe and effective for patients who were already taking newer blood thinners when their stroke happened. Researchers will follow 260 stroke patients in Hong Kong who took their last dose of…

This study is testing if more frequent monitoring and quicker adjustments to cholesterol-lowering medication can help heart disease patients reach their treatment goals. It will enroll 1,000 adults with heart disease to see if this approach lowers 'bad' cholesterol more effective…

This study aims to find the best endoscopic method to remove small, early-stage stomach tumors called GISTs. It will compare two minimally invasive techniques—EFTR and STER—to see which one more completely removes the tumor while keeping patients safe. About 136 adults with small…

This study is testing whether an online therapy program for social anxiety disorder works just as well when guided by a trained coach instead of a clinical psychologist. It aims to make effective treatment more accessible and affordable. About 110 adults in Hong Kong with social …

This study is testing a simpler, lower-cost method to help eggs mature outside the body for women with infertility. It aims to help women who have trouble getting pregnant naturally, including those who need to preserve their fertility before cancer treatment. The method is desig…

This study is testing a new skin test to find hidden tuberculosis (TB) in people with arthritis before they start certain powerful arthritis medications. Researchers will compare the new test to standard tests in 100 patients to see how well it works. The goal is to improve early…

This study is testing a new artificial intelligence (AI) tool designed to automatically spot and measure aortic regurgitation, which is a leak in the heart's main valve. It will compare the AI's accuracy and speed against the standard method where doctors manually analyze heart u…

This study is testing a new blood test called HerResolve™ that aims to detect endometriosis without surgery. Researchers will compare the blood test results to findings from laparoscopic surgery in 100 women aged 18-49 who have pelvic pain symptoms. The goal is to see if this non…

This study is testing a new, very fast type of MRI scan designed to detect early liver scarring (fibrosis) without the need for a painful biopsy. Researchers will compare the scan's results to both the current gold-standard biopsy and another non-invasive scan in 200 adults with …

This small pilot study is testing whether a camera procedure to check for returning kidney cancer can be done safely using only local numbing gel, without putting patients to sleep with general anesthesia. It will involve 10 people who have previously had surgery to remove a spec…

This study is comparing two different methods for performing prostate biopsies in men who have a suspicious area on an MRI scan. It aims to find out which method—using a computer to fuse the MRI with ultrasound images or relying on the doctor's mental map—is better at finding ser…

This study is testing whether a simple program can help people visiting the emergency room start living healthier to prevent future chronic diseases. Over 1,100 participants will receive brief health advice and then get weekly text or app messages with reminders and short videos …

This study is testing a digital sleep program designed to prevent chronic insomnia in adults who currently have only mild sleep problems. Over 1,000 adults in Hong Kong will use an online platform that offers different levels of sleep coaching based on their needs. The goal is to…

This study offers ovarian tissue freezing to young female cancer patients (ages 0-35) to preserve their ability to have children later in life. The procedure is designed for patients who need to start cancer treatments like chemotherapy or radiation immediately, as it does not re…

This study is testing whether a brief therapy session delivered by an artificial intelligence therapist in virtual reality can help reduce symptoms of depression. It will involve 60 young adults in Hong Kong who report depressive symptoms, comparing the VR therapy to a waiting li…

This study is testing whether a specific nerve block, given during surgery, can improve recovery and reduce the chance of developing long-term pain after heart surgery. Researchers will compare the nerve block to a placebo in 96 adults having planned heart operations. The main go…

This study is testing a mobile phone app designed to help children who have finished cancer treatment manage their ongoing symptoms like fatigue, pain, and anxiety. For 12 weeks, 150 child survivors and their main caregiver will use the app, which includes personalized support fr…

This study is testing whether a fun, game-like music training program can help children from low-income families cope better with stress. 174 children aged 8 to 12 who are at risk for anxiety or depression will be randomly assigned to either take weekly music lessons or participa…

This study is testing a new soft robotic glove designed to help people recover hand and arm movement after a stroke. Sixty stroke survivors will attend training sessions where the glove assists them with different tasks, using their own muscle signals to guide the movement. The g…

This study is testing whether whole-body vibration therapy can help reduce knee pain and improve muscle strength in people who have had surgery to repair a torn ACL. Researchers will enroll 50 adults who have persistent knee pain after their ACL surgery. The goal is to see if thi…

This study is testing whether daily bright light therapy can help improve depression in teenagers who naturally stay up late and sleep in. 90 teens will use either a bright light lamp or a dim placebo lamp each morning for 8 weeks. Researchers will track changes in their mood, sl…

This study is testing if a special, non-needle electrical stimulation device can reduce pain by 50% for women undergoing egg retrieval as part of IVF. 144 women will be randomly assigned to use either the real device or a fake one during the procedure to see which works better. T…

This study is testing a new nurse-led program designed to help children with cancer sleep better. The program teaches kids and their caregivers relaxation exercises and healthy sleep habits, aiming to improve their quality of life during treatment. It's a small pilot study to see…

This study aims to observe and collect information on 500 adults in Hong Kong who have severe, difficult-to-treat asthma. Researchers will track their symptoms, current treatments (including newer, expensive biologic drugs), and how often their asthma worsens over two years. The …

This research study aims to find better treatments for children with leukemia. Researchers will test leukemia cells from 300 children against various targeted drugs to see which ones work best. They will also develop and test new antibody treatments in lab models to prepare for f…

This study aims to understand how the community of bacteria and viruses in the nose and throat is connected to different types and severities of asthma in adults. Researchers will collect swabs from 140 adults with asthma and track their health over two years. The goal is to gath…

This study aims to follow 5000 adults over many years to understand what factors lead to brain diseases like stroke and dementia. It will track people who already have a diagnosis, are at high risk, or are currently healthy, using questionnaires and medical records. The goal is t…

This study aims to understand what women in Hong Kong know about common gynecological problems and what stops them from getting help. Researchers will survey 800 people, including patients and the general public, to compare their knowledge and identify barriers to care. The goal …

This study aims to better understand which fatty deposits (plaques) in brain arteries are most likely to break off and cause a stroke. Researchers will compare detailed brain scans from 140 people who have had a stroke with scans from people who have similar plaques but no sympto…

This study aims to see if a simple blood test can tell doctors how well radiation therapy is working for liver cancer. Researchers will track tiny pieces of cancer DNA in the blood of 15 patients before, during, and after their radiation treatment. The goal is to find a better, f…

This study aims to understand if COVID-19 vaccines affect brain health, specifically looking for signs of stroke or dementia. Researchers in Hong Kong will follow 500 healthy adults, comparing brain scans and memory tests from before and after vaccination to those from unvaccinat…

This study aims to understand how protection against COVID-19 changes within families over time. Researchers will follow 900 households in Hong Kong for 12-18 months, checking blood for antibodies from vaccines and past infections. The goal is to learn how immunity levels in a ho…

This study aims to understand how well a proven emergency stroke treatment works in everyday hospital practice across the Asia-Pacific region. Researchers will follow 350 adult stroke patients to see what factors help or hinder successful treatment in real-world settings, compare…

This study is building a collection of blood and tissue samples from stroke patients. The goal is to store these samples for future research to better understand the genetic causes of stroke. Researchers hope this 'biobank' will help scientists discover new ways to prevent and tr…

This study looks back at medical records to understand how biologic drugs are used to treat severe asthma in Hong Kong. Researchers will review the health data of 360 adults who received these treatments to see how well they worked and how safe they were. The goal is to learn abo…

This study aims to create a detailed registry of 1000 people in Hong Kong who have both Type 2 diabetes and fatty liver disease (MASLD). Researchers will follow participants over time to understand how these two common conditions affect each other and progress. The main goal is t…

This study aims to develop a computer prediction tool to identify which patients with chronic lung disease (COPD) are most likely to be readmitted to the hospital soon after being discharged. Researchers will analyze the health records of 100,000 patients in Hong Kong using machi…

This study aims to create a detailed health register to understand how diabetes and obesity together affect people's long-term health. It will follow 800 adults in Hong Kong with both conditions, conducting thorough health checks at the start and again after 3 years. The main goa…

This study aims to create a better system for developing safety guidelines about mixing herbal remedies and prescription drugs. Researchers will gather opinions from 40 healthcare experts and policymakers through surveys and interviews. The goal is to understand current challenge…

This study aims to understand how plaque inside the brain's arteries changes shape and size over one year in people who have had a stroke. Researchers will use a detailed 3D imaging scan at the start and after 12 months to closely measure these changes. The goal is to learn more …

This study aims to understand how genetics influence asthma severity and types in Chinese people. Researchers will collect blood samples and health information from 1000 asthma patients and 1000 healthy volunteers. The goal is to identify specific genetic patterns that make some …

This study aims to understand how well different fertility preservation methods work for people whose medical treatments (like cancer therapy) might affect their future ability to have children. Researchers will review the medical records of up to 100 patients who have used these…