Can One-Piece tumour removal improve bladder cancer outcomes?

NCT ID NCT04934540

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This global registry is collecting data on a surgical technique called en bloc resection of bladder tumour (ERBT), which removes the tumour in one piece rather than in fragments. The goal is to see whether this approach leads to complete tumour removal and better recurrence-free survival in bladder cancer patients. Over a 5-year period, researchers will track outcomes in about 2,000 adults undergoing ERBT. The findings could help clarify the role of this technique in managing bladder cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
En bloc resection of bladder tumour (ERBT), a surgical technique that removes the tumour in one piece
What this could lead to
If successful, this registry could clarify whether ERBT improves complete tumour removal and reduces recurrence in bladder cancer, potentially guiding future surgical standards.
What could go wrong
As a registry, it only observes outcomes without a control group, so it cannot prove ERBT is better than standard surgery. Results may also vary across global sites.

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Conditions

The condition(s) this trial relates to.

urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • North District Hospital

    RECRUITING

    Hong Kong, Hong Kong

  • Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong

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