AI could spot lung cancer in Non-Smokers with family history

NCT ID NCT06295497

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether an artificial intelligence program can help detect lung cancer early in non-smokers aged 50 to 75 who have a close family member with lung cancer. About 3,000 participants will get a low-dose CT scan of their chest, and the AI will analyze the images for suspicious nodules. If the AI finds a nodule, doctors will follow up to check if it is cancer. The goal is to see if AI can make lung cancer screening practical and accurate for this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Artificial intelligence software (Lung-SIGHT) to analyze low-dose CT scans

What this could lead to

If successful, this could provide a practical, AI-driven screening method to detect lung cancer early in non-smokers with a family history, potentially saving lives through earlier treatment.

What could go wrong

This is an early feasibility study with no control group, so results may not prove the AI is better than standard care. The AI might miss some cancers or flag too many false alarms, leading to unnecessary procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Clinical Oncology, Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••