Chinese University Of Hong Kong

This pilot study tests a temporary, flexible tube called a duodenal-jejunal bypass sleeve. It is placed in the upper intestine using an endoscope and left for 3 months to help with weight loss and improve metabolic syndrome. The study involves 20 adults with obesity or excess wei…

This study tests whether Maraviroc, a drug currently used for HIV, can reduce muscle inflammation and improve function in adults with myositis that hasn't responded to standard treatments. Ten participants will take a daily 300mg tablet for 12 weeks and undergo muscle biopsies an…

This study tests a procedure called pulsENDO that uses mild electric pulses to regenerate the lining of the first part of the small intestine (duodenum) in people recently diagnosed with type 2 diabetes. The goal is to see if this can help control blood sugar levels without needi…

This study tests whether using MRI and AI to guide steam therapy can improve treatment for an enlarged prostate (BPH). Men aged 30-80 with moderate symptoms and a prostate size between 30-80 mL are eligible. All participants receive the standard steam procedure, but with added MR…

This study tests a procedure called pulsENDO that uses mild electric pulses to regenerate the lining of the duodenum (the first part of the small intestine). The goal is to improve blood sugar control and reduce fat buildup in the liver for people with type 2 diabetes and fatty l…

This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) can reduce brain swelling and improve recovery in people who have had a bleeding stroke. About 200 adults with a specific type of brain bleed will receive either standard care or the drug plus standar…

This study tests whether mixing a woman's own platelet-rich plasma (PRP) with her partner's sperm before intrauterine insemination (IUI) can increase pregnancy rates. About 288 women with infertility will be randomly assigned to receive either standard IUI or IUI with PRP-treated…

This study will follow 100 adults with von Hippel-Lindau (VHL) disease who choose to take belzutifan. Researchers will track how well the drug shrinks tumors, its side effects, and its impact on quality of life and healthcare costs. The goal is to better understand the drug's rea…

This study tests a 3-month behavioral coaching program for 232 adults with coronary heart disease who sit a lot. The program includes face-to-face and phone sessions to help them reduce sitting time and increase physical activity. Researchers will measure changes using activity t…

This study tests whether a single dose of the RSV vaccine (Arexvy) can reduce moderate-to-severe COPD flare-ups in people who have frequent attacks. Researchers will enroll 320 high-risk patients aged 50+ and follow them for one year. Half will get the vaccine plus standard care,…

This study compares two surgical methods for acute Type A aortic dissection, a life-threatening tear in the main artery. One method is the standard hemiarch replacement, and the other is a more complex total arch replacement with a frozen elephant trunk device. Researchers will e…

This pilot study tests a new synbiotic formula (SGR11) in 50 adults with mild-to-moderate ulcerative colitis, a type of inflammatory bowel disease. Participants take the supplement daily for 8 weeks. Researchers will check if symptoms improve and if the supplement is safe, using …

This study tests a 6-week program designed for people with high blood pressure who have low health literacy. Participants attend group sessions and get phone coaching to learn how to manage their condition. The goal is to see if this approach can lower blood pressure better than …

This study tests whether taking a laxative (bisacodyl) for two days before getting a peritoneal dialysis catheter can prevent blockages. About 398 adults needing dialysis will be randomly assigned to receive the laxative or usual care. The goal is to see if this simple step reduc…

This study tests whether mixing a woman's own platelet-rich plasma (PRP) with her partner's sperm before intrauterine insemination (IUI) can increase the chance of pregnancy. About 288 women with infertility will be randomly assigned to receive either PRP-treated sperm or standar…

This study tests whether semaglutide (Ozempic), a drug used for diabetes and weight loss, can slow the buildup of plaque in arteries of people with psoriatic arthritis who do not have diabetes. Forty participants will receive either semaglutide or no additional treatment for 24 w…

This study tests whether adding a very low dose of the steroid prednisolone (4 mg daily for 4 weeks, then tapering off) to standard treatment helps control symptoms in people newly diagnosed with active rheumatoid arthritis. About 112 adults will be randomly assigned to receive e…

This study tests a temporary pacing technique to slow dangerously fast heart rates in people with atrial fibrillation who cannot use standard medications. Researchers will pace specific nerve fibers near the heart to see if it safely controls heart rate without permanent procedur…

This study tests whether a mix of 11 Chinese herbs, called Modified Qing-Zao-Jiu-Fei Decoction, can help people with pneumoconiosis (a lung disease from inhaling dust). Eighty adults aged 20-85 will receive either the herb granules or a placebo for 16 weeks. The main goal is to s…

This study tests whether combining a risk score (ADD-RS) with a D-dimer blood test can safely rule out acute aortic syndrome (a life-threatening tear in the aorta) in emergency room patients. About 448 adults with symptoms like chest or back pain will be enrolled. If the combinat…

This study looks at whether adding a special PET scan (18F-PSMA) to an MRI can find more serious prostate cancers in men whose MRI results are unclear. About 250 men with suspicious but not definitive MRI scans will be randomly assigned to get either an MRI-guided biopsy alone or…

This study tests a new liquid biopsy that measures TB DNA in fluid from around the lungs to diagnose tuberculous pleuritis, a common form of TB. Current methods often require invasive tissue biopsies or have low accuracy. The trial will enroll 350 adults with new-onset pleural ef…

This study tests a new blood test that looks for TB DNA in the blood. It aims to see if it works as well as a bronchoscopy (a scope down the throat) to diagnose lung tuberculosis. 600 adults who need a bronchoscopy will give a blood sample for comparison. If successful, patients …

This study tests whether a digital program that combines cognitive behavioral therapy for insomnia with circadian rhythm coaching can prevent depressive symptoms from worsening in college students aged 18-24 who have trouble falling asleep and tend to be night owls. Participants …

This study tests whether a 6-week dance-based exercise program can reduce nerve pain and improve quality of life in cancer patients who have nerve damage from chemotherapy. About 76 adults with solid tumors will either join the dance program or receive usual care. The goal is to …

This study tests if fezolinetant can reduce hot flashes in men receiving hormone therapy for prostate cancer. About 54 men will take either the drug or a placebo, and track their hot flash severity and quality of life. The goal is to ease this common side effect without affecting…

This study looks at whether a 6-week mindfulness program can improve well-being, reduce stress, and boost job performance for hotel employees. About 60 hotel staff in Hong Kong will take part. Researchers will measure changes in emotional labor, burnout, job satisfaction, and str…

This pilot study will test a 12-week telehealth program for frail adults aged 65+ who have just left the hospital. The program includes weekly video sessions with exercise, self-management tips, and peer support, plus activity sensors to track movement. Researchers want to see if…

This study tests whether a Mediterranean diet, adapted for Hong Kong, can reduce depression symptoms in 90 adults with moderate to severe depression. Participants will receive meal deliveries and track their mood and diet via phone surveys. The study also looks at how gut bacteri…

This study tests a gentle, non-invasive brain stimulation technique called so-tDCS in 80 older adults who have mild memory and sleep complaints. Participants will receive either real or sham stimulation over 4 weeks. Researchers will track changes in memory, sleep quality, and br…

This study tests whether adding pure platelet-rich plasma (P-PRP) to sperm samples can improve sperm movement (motility) in a lab. Researchers will first standardize how to make P-PRP, then compare sperm quality after 24 hours with and without P-PRP. The trial involves 248 partic…

This study tests whether a 5-week nostalgia program can reduce loneliness in older adults living in the community. 294 participants aged 60+ in Hong Kong will join small group sessions using music, photos, and meaningful objects to spark positive memories. The goal is to see if t…

This study tests a smartphone app called GoodShleep that gives personalized sleep and circadian tips in real time. It includes a wearable to track sleep and activity, plus mood check-ins. Researchers will first optimize the app with 77 adults in Hong Kong who have sleep or circad…

This study tests a smartphone app called GoodShleep+ that gives personalized, in-the-moment suggestions to help people with sleep and circadian problems. About 80 adults in Hong Kong will either use the app for 8 weeks or continue their usual care. The goal is to see if the app i…

This study tests whether myofunctional therapy—simple exercises for the tongue, face, and breathing muscles—can improve sleep in children aged 6-12 with obstructive sleep apnea. Half of the 174 participants will do these exercises for 24 weeks with remote coaching, while the othe…

This study tests whether taking butyrate and taurine supplements daily can prevent chronic pain after heart surgery. 216 adults having elective heart surgery will receive either the supplements or a placebo for three months after their operation. Researchers will track pain level…

This online study with 2,800 Hong Kong adults tests whether front-of-package warning labels about added sugar reduce people's intention to buy sugary drinks. Participants will choose a beverage in a simulated shopping task. The goal is to see if simple labels can guide healthier …

This pilot study will test whether a flexible scope inserted into the urinary tract (ureterorenoscopy) under local anesthesia is safe and feasible for monitoring upper tract urothelial cancer in 10 people who have had kidney-sparing surgery. The main goal is to see if the procedu…

This study tests a new robotic system (Intilume) for removing early-stage rectal tumors through the body's natural openings, avoiding incisions. Ten adults with non-cancerous or early cancerous growths in the rectum will be treated. The goal is to see if the robot makes the proce…

This study will test a new single-port surgical robot, called SHURUI, for chest surgeries like removing lung tumors or mediastinal masses. About 40 adults aged 18-75 who need these surgeries will take part. The goal is to see if the robot is safe and works well, with hopes of les…

This study tests whether a chatbot that gives personalized advice can help men who have sex with men reduce chemsex (using drugs before or during sex). About 100 men in Hong Kong will be split into two groups: one gets weekly videos on chemsex risks, and the other gets the same v…

This study will test a new robotic surgical system, the Sentire Surgical System with a new Patient Side Single Arm, in 12 people needing colorectal surgery for cancer or large polyps. The goal is to see if the system is safe and effective, and if it can reduce costs compared to c…

This study follows 160 adults in Hong Kong over time to see if disruptions in daily activity and sleep (rest-activity rhythms) can predict who develops major depressive disorder. Participants will wear activity monitors and complete questionnaires about mood and sleep. The goal i…

This study looks at 150 adults hospitalized for a COPD flare-up to find hidden heart and kidney problems. Researchers will use a special discharge care plan and compare readmission rates to past patients. The goal is to understand how often these hidden issues occur and improve f…

This study follows 100 young cancer patients (ages 0-18) who freeze their ovarian tissue before treatment. Researchers want to see how safe the procedure is and how many go on to have a baby after transplanting the tissue back. The goal is to learn if this method effectively pres…

This study will track 10,000 adults in Hong Kong with respiratory symptoms to measure how often RSV causes illness and how severe it gets. Researchers will collect nose and throat samples and blood tests over several weeks. The goal is to fill knowledge gaps about RSV in adults a…

This long-term research registry will follow 200 adults—both those with Achilles tendon problems and healthy volunteers—to understand which treatments work best and why. Participants undergo physical tests, ultrasounds, and questionnaires over the first year, then annual online c…

This study uses machine learning to predict how well people recover after ACL surgery. Researchers will measure muscle strength and size, along with other factors, to identify patients who may not respond well to standard rehabilitation. The goal is to create a tool that helps do…

This study will use artificial intelligence and 3D CT scans to predict how well a person's lungs will work after different treatments for early-stage lung cancer. About 192 adults with stage IA non-small cell lung cancer will be followed for two years after surgery or a minimally…