Chinese University Of Hong Kong

This small pilot study aims to see if adding a drug called fludrocortisone to standard treatment helps patients survive septic shock, a deadly condition where infection causes dangerously low blood pressure. The study will involve 32 critically ill patients in intensive care unit…

This study is testing a new, one-time endoscopic procedure that uses electrical pulses to modify the lining of the small intestine. The goal is to see if this can help people recently diagnosed with type 2 diabetes control their blood sugar without needing daily diabetes medicati…

This pilot study is testing whether a 12-week telehealth support program can help frail older adults recover better after a hospital stay. The program provides weekly video sessions and uses activity sensors to encourage movement and monitor progress. Researchers will enroll 50 p…

This pilot study is testing whether a daily synbiotic formula called SGR11 can help improve symptoms and gut health in people with inflammatory bowel disease (IBD). Fifty adults with mild to moderate ulcerative colitis will take the formula for 8 weeks while researchers track the…

This study is testing a new robotic system designed to help surgeons perform kidney stone removal surgery. The system, called TaloStone T1000, uses AI and remote controls to assist with navigating inside the kidney and handling surgical tools. The goal is to see if this robotic a…

This study is testing if a new step can help couples get pregnant through IUI. Researchers will mix a small amount of the woman's own processed blood (called PRP) with her husband's sperm before the IUI procedure to see if it improves the chance of pregnancy. They will compare pr…

This study is the world's first multi-center trial to compare two major surgeries for a life-threatening tear in the body's main artery (acute Type A aortic dissection). It will enroll 150 patients to see if a newer, more complex procedure (TARFET) leads to better 30-day survival…

This study is testing if adding a very low daily dose of the steroid prednisolone to standard treatment helps people newly diagnosed with active rheumatoid arthritis. Over 12 weeks, 112 participants will receive either the steroid or a placebo pill, while also starting standard a…

This study is testing if giving patients a laxative before surgery to insert a dialysis catheter helps prevent the catheter from getting blocked afterward. Blocked catheters are a common problem that can require extra procedures to fix. Researchers will compare results in about 4…

This study is testing whether a therapy involving mouth, tongue, and breathing exercises can help children with obstructive sleep apnea (OSA). Researchers will enroll 174 children aged 6-12 and randomly assign them to either receive the exercise therapy or standard care. The main…

This study is testing if a 12-week chatbot program can help men who have sex with men in Hong Kong reduce the use of drugs during sex (chemsex) and lower their risk for HIV. About 100 participants will be randomly assigned to either use the chatbot or just watch weekly educationa…

This study will test a new, more affordable robotic surgery system for removing colorectal cancer and large polyps. Researchers want to see if this system works as well as the current expensive option, with similar safety and results. The study will involve 12 patients undergoing…

This study is testing a coaching program designed to help people with coronary heart disease sit less and be more active. About 232 participants will be randomly assigned to receive either the coaching sessions plus usual care, or just usual care. The main goal is to see if the p…

This study is testing whether a 6-week education program can help people with high blood pressure and low health literacy better manage their condition. The program includes three in-person sessions and three phone calls, providing tailored information about blood pressure manage…

This study is testing a new, one-time endoscopic procedure called ReCET for people whose type 2 diabetes is not well-controlled with pills. The goal is to see if treating the first part of the small intestine (duodenum) can improve blood sugar levels and reduce fat in the liver. …

This study is testing a temporary pacing method to slow dangerously fast heart rates in people with atrial fibrillation (a common irregular heartbeat) who cannot use standard medications. Researchers will place a temporary pacing wire near specific heart nerves to see if gentle e…

This study follows young girls (ages 0-18) with cancer who have frozen a piece of their ovarian tissue before treatment. The goal is to see if transplanting this tissue back later is safe and can lead to successful pregnancies. Researchers will track surgical complications and pr…

This study is testing if a GLP-1 receptor agonist drug (semaglutide) can help control hidden heart disease risk in people with psoriatic arthritis who do not have diabetes. It will enroll 40 participants to see if the drug can slow the progression of artery thickening and stiffne…

This study is testing a new, personalized brain stimulation device to see if it can help older adults who are worried about their memory and have trouble sleeping. Researchers will compare the real device to a fake one in 80 participants over 12 weeks to measure effects on memory…

This study is testing a new robotic system designed to help surgeons remove early-stage rectal tumors more precisely and easily. The procedure is performed entirely through the body's natural opening, aiming to avoid external cuts. Researchers will measure how completely the tumo…

This study aims to validate a new blood test that detects tuberculosis (TB) DNA as a safer, faster alternative to bronchoscopy for diagnosing lung TB. It will involve 600 adults in Hong Kong who need a bronchoscopy but cannot provide a good sputum sample. The goal is to see if th…

This study is testing a new, less invasive method to diagnose tuberculous pleuritis, a common form of tuberculosis that affects the lining of the lungs. Researchers will enroll 350 adults with new fluid buildup around one lung to see if a simple fluid test can accurately detect T…

This study is testing a new, non-invasive blood and urine test to diagnose tuberculosis (TB) and monitor treatment. It aims to provide a faster, easier alternative to current methods like sputum samples or invasive biopsies, which can be difficult for some patients. Researchers w…

This study aims to find a better way to detect serious prostate cancer in men whose initial MRI scans are unclear. Researchers will compare two approaches: one using only MRI to guide a biopsy, and another that adds a special PET scan called 18F-PSMA. The goal is to see if the co…

This study is testing whether taking two common supplements, butyrate and taurine, can prevent patients from developing long-term pain after major heart surgery. It will involve 216 adults who will take the supplement combination or a placebo daily, starting the day before surger…

This study aims to test whether platelet-rich plasma (PRP) made from donated blood can improve sperm quality in men with infertility. Researchers will first develop a standard method to prepare the PRP, then test if adding it to sperm samples increases their movement and health. …

This study is testing a smartphone app designed to help people with ongoing sleep problems. The app sends personalized, timely suggestions for improving sleep habits, based on data from a wearable device. Researchers will compare how well these personalized tips work compared to …

This study aims to see if personalized lifestyle coaching helps older adults better manage long-term muscle and joint pain. Researchers will compare a group receiving coaching sessions to a group receiving usual care. They will measure changes in pain levels, daily function, stre…

This study is testing whether a simple genetic test can help doctors choose the most effective anti-nausea medication for patients. It involves 200 Chinese women with early breast cancer who are about to start their first round of a specific chemotherapy. Half will get anti-nause…

This study is testing if practicing exercises with nunchaku (a martial arts training tool) is more helpful and enjoyable than standard exercises for people with frozen shoulder. Researchers will compare the two approaches in 50 middle-aged and older adults over 12 weeks. The main…

This study is testing whether group sessions focused on sharing nostalgic memories can help reduce feelings of loneliness in older adults living at home. Researchers will enroll 294 participants in Hong Kong, who will either join five weekly nostalgia sessions or be placed on a w…

This study is testing a smartphone app designed to help people with ongoing sleep problems. It will compare whether sending personalized, timely suggestions is more effective than sending generic messages or no messages at all. The goal is to see if the app can improve sleep qual…

This study is testing whether following a Mediterranean diet, adapted for Hong Kong Chinese culture, can help reduce symptoms of depression. Researchers will enroll 90 adults with moderate depression and track their diet, mood, and gut bacteria over time. The goal is to see if im…

This study is testing whether a modified traditional Chinese herbal formula can help people with pneumoconiosis, a serious lung scarring disease often caused by dust exposure. Researchers will give 80 participants either the herbal granules or a placebo for 16 weeks to see if it …

This study aims to see if a computer program (machine learning) can predict how well someone will recover after ACL knee surgery. Researchers will track 182 patients for a year after their operation, measuring their muscle strength and size. The goal is to identify patients early…

This study evaluates a new single-port surgical robot called SHURUI SP for performing chest surgeries. Researchers will measure how safe and effective the robot is for lung and chest tumor removal procedures in 40 patients. The study focuses on surgical outcomes, complication rat…

This study aims to identify which factors are linked to successful pregnancies in couples undergoing intrauterine insemination (IUI). Researchers will look back at data from about 3000 IUI cycles to see how hormone levels, sperm quality, and other details relate to pregnancy outc…

This study is creating a long-term registry to track people with Achilles tendon injuries and healthy adults. Researchers will collect detailed information through hospital visits and online questionnaires over five years. The goal is to understand which treatments work best for …

This study aims to measure how often and how severely Respiratory Syncytial Virus (RSV) affects adults in Hong Kong. Researchers will enroll up to 10,000 adults with respiratory symptoms to collect samples and track health outcomes. The goal is to get a clearer picture of RSV's t…

This study aims to use artificial intelligence (AI) to predict how well patients' lungs will recover after surgery for early-stage lung cancer. Researchers will combine 3D lung scans and breathing test results to create a predictive score. They will compare recovery between three…

This study aims to understand if the level of the hormone progesterone in the blood on the day a frozen embryo is transferred is linked to the chance of achieving a clinical pregnancy. Researchers will observe about 370 women undergoing frozen embryo transfer cycles using hormone…

This study aims to find out how many people hospitalized for a COPD flare-up also have hidden heart or kidney problems. Researchers will screen 150 patients in Hong Kong for these conditions at discharge and provide a care package with follow-up. The goal is to understand the ris…

This study aims to understand if a person's daily rest and activity patterns, measured by a wrist-worn device, can predict who develops major depression or whose symptoms get worse. Researchers will follow 160 adults in Hong Kong over time, tracking their sleep, mood, and activit…