Can removing bladder tumors in one piece improve cancer outcomes?

NCT ID NCT07724886

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether a newer surgical method called en bloc resection, which removes bladder tumors in one piece, works better than the standard piecemeal approach for people with intermediate- or high-risk non-muscle-invasive bladder cancer. All participants also receive a year of intravesical BCG immunotherapy. The study aims to see which technique leads to fewer cancer recurrences.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
transurethral en bloc resection of bladder tumour plus intravesical bacillus Calmette-Guerin therapy
What this could lead to
If en bloc resection proves superior, it could become the new standard surgical approach for intermediate- and high-risk non-muscle-invasive bladder cancer, potentially reducing recurrence rates.
What could go wrong
This is a large but early-stage comparison; the new technique may not improve outcomes over the standard approach and could carry different surgical risks.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • North District Hospital

    Sheung Shui, Hong Kong

    Contact Email: •••••@•••••

  • Prince of Wales Hospital

    Hong Kong, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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