A reversible gut sleeve could offer a new way to treat obesity

NCT ID NCT07675122

Not yet recruiting Disease control Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This pilot study tests a temporary, flexible tube called a duodenal-jejunal bypass sleeve. It is placed in the upper intestine using an endoscope and left for 3 months to help with weight loss and improve metabolic syndrome. The study involves 20 adults with obesity or excess weight plus metabolic syndrome. Researchers will measure weight loss, body fat changes, and safety over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: duodenal-jejunal bypass sleeve
What this could lead to: If successful, this could offer a less invasive, reversible alternative to gastric bypass surgery for weight loss and metabolic syndrome.
What could go wrong: This is a small pilot study with only 20 participants, so results may not apply broadly. The sleeve is temporary (3 months) and long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome metabolic syndrome X Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METABOLIC SYNDROME (METS) OBESITY

Contacts and locations

Locations

CUHK Medical Centre

Shatin, Hong Kong
Chinese University of Hong Kong

Shatin, Hong Kong

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