A reversible gut sleeve could offer a new way to treat obesity

NCT ID NCT07675122

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This pilot study tests a temporary, flexible tube called a duodenal-jejunal bypass sleeve. It is placed in the upper intestine using an endoscope and left for 3 months to help with weight loss and improve metabolic syndrome. The study involves 20 adults with obesity or excess weight plus metabolic syndrome. Researchers will measure weight loss, body fat changes, and safety over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

duodenal-jejunal bypass sleeve

What this could lead to

If successful, this could offer a less invasive, reversible alternative to gastric bypass surgery for weight loss and metabolic syndrome.

What could go wrong

This is a small pilot study with only 20 participants, so results may not apply broadly. The sleeve is temporary (3 months) and long-term benefits are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome metabolic syndrome X Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CUHK Medical Centre

    Shatin, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chinese University of Hong Kong

    Shatin, Hong Kong

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact