Microwave ablation vs. radiotherapy: which Non-Surgical option works best for early lung cancer?
NCT ID NCT07722182
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This trial compares two treatments for early-stage lung cancer in patients who cannot have surgery: microwave ablation delivered through a bronchoscope versus standard stereotactic body radiotherapy. The goal is to see which approach better controls the tumor over two years, with fewer side effects and less burden on patients. One hundred participants will be randomly assigned to one of the two treatments and monitored with regular CT scans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- navigation bronchoscopy-guided microwave ablation or stereotactic body radiotherapy
- What this could lead to
- If one treatment proves better or less burdensome, it could become a new standard option for patients with early-stage lung cancer who cannot undergo surgery.
- What could go wrong
- This is a phase 2 trial with only 100 participants, so results may not be definitive. Both procedures carry risks such as bleeding, infection, or radiation side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Prince of Wales Hospital
Hong Kong, Hong Kong
Contact Phone: •••-•••-•••• Email: •••••@•••••
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