Can two common supplements stop chronic pain after heart surgery?

NCT ID NCT07144033

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether taking butyrate and taurine supplements daily can prevent chronic pain after heart surgery. 216 adults having elective heart surgery will receive either the supplements or a placebo for three months after their operation. Researchers will track pain levels, recovery quality, and side effects to see if this simple approach helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

butyrate and taurine (dietary supplements)

What this could lead to

If it works, this could offer a simple, safe supplement routine to prevent long-term pain after heart surgery, reducing reliance on opioids.

What could go wrong

This is a phase 2 trial with only 216 participants, so results may not apply to everyone. The supplements might not reduce pain more than placebo, and long-term effects are still unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain Chronic Pain chronic pain syndrome Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Prince of Wales Hospital

    Hong Kong, Hong Kong