Can two common supplements stop chronic pain after heart surgery?

NCT ID NCT07144033

Not yet recruiting Symptom relief Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether taking butyrate and taurine supplements daily can prevent chronic pain after heart surgery. 216 adults having elective heart surgery will receive either the supplements or a placebo for three months after their operation. Researchers will track pain levels, recovery quality, and side effects to see if this simple approach helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: butyrate and taurine (dietary supplements)
What this could lead to: If it works, this could offer a simple, safe supplement routine to prevent long-term pain after heart surgery, reducing reliance on opioids.
What could go wrong: This is a phase 2 trial with only 216 participants, so results may not apply to everyone. The supplements might not reduce pain more than placebo, and long-term effects are still unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acute Pain Chronic Pain chronic pain syndrome Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC POST OPERATIVE PAIN PAIN, ACUTE PAIN, CHRONIC

Contacts and locations

Locations

Prince of Wales Hospital

Hong Kong, Hong Kong

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