Can a needle through the windpipe beat the knife for early lung cancer?

NCT ID NCT07741344

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial tests whether a minimally invasive procedure called bronchoscopic microwave ablation can be as effective as surgery for early-stage lung cancer (stage IA). The procedure uses a bronchoscope to guide a needle to the tumor and destroy it with heat, potentially preserving more lung tissue. The study will compare disease-free survival, lung function, and quality of life between the two approaches in about 292 adults.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Bronchoscopic microwave ablation
What this could lead to
If successful, this could establish a less invasive, lung-sparing option for early-stage lung cancer, potentially reducing recovery time and preserving lung function.
What could go wrong
The trial is in Phase 2, and the ablation may not control the cancer as well as surgery. There are risks of incomplete ablation or complications from the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Prince of Wales Hospital

    Hong Kong, Hong Kong