New surgery may save more lives from deadly aortic tear

NCT ID NCT06676371

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two surgical methods for acute Type A aortic dissection, a life-threatening tear in the main artery. One method is the standard hemiarch replacement, and the other is a more complex total arch replacement with a frozen elephant trunk device. Researchers will enroll 150 adults in Hong Kong to see which approach leads to better 30-day survival. The goal is to find the best way to treat this emergency and reduce deaths.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
surgical procedure (total arch replacement with frozen elephant trunk or conventional hemiarch replacement)
What this could lead to
If it works, this could establish a better surgical approach for a life-threatening aortic tear, potentially lowering the risk of death within 30 days.
What could go wrong
This is an early-stage randomized trial with 150 participants, so results may not apply to all patients. Both surgeries are complex and carry risks like bleeding, stroke, or organ failure.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Prince of Wales Hospital

    Hong Kong, Hong Kong

  • Siriraj Hospital - Mahidol University

    Bangkok, Thailand

  • University Hospital Vienna

    Vienna, Austria

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