New surgery may save more lives from deadly aortic tear

NCT ID NCT06676371

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two surgical methods for acute Type A aortic dissection, a life-threatening tear in the main artery. One method is the standard hemiarch replacement, and the other is a more complex total arch replacement with a frozen elephant trunk device. Researchers will enroll 150 adults in Hong Kong to see which approach leads to better 30-day survival. The goal is to find the best way to treat this emergency and reduce deaths.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surgical procedure (total arch replacement with frozen elephant trunk or conventional hemiarch replacement)

What this could lead to

If it works, this could establish a better surgical approach for a life-threatening aortic tear, potentially lowering the risk of death within 30 days.

What could go wrong

This is an early-stage randomized trial with 150 participants, so results may not apply to all patients. Both surgeries are complex and carry risks like bleeding, stroke, or organ failure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Prince of Wales Hospital

    Hong Kong, Hong Kong

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Siriraj Hospital - Mahidol University

    Bangkok, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospital Vienna

    Vienna, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact