Chinese University Of Hong Kong

This study tested a powerful chemotherapy combination (FOLFOXIRI) followed by radiation with capecitabine before surgery in 40 people with high-risk rectal cancer. The goal was to shrink tumors and make surgery more successful. The approach aims to control the disease and reduce …

This study tests whether trazodone, a medication used for sleep, can slow down memory loss and brain changes in people with mild cognitive impairment and obstructive sleep apnea. About 134 participants will take either trazodone or a placebo for one year. Researchers will measure…

This study looks at 70 liver cancer patients who had bleeding from enlarged veins in the esophagus. It compares two procedures—an ultrasound-guided glue injection and a standard banding technique—to see which better prevents future bleeding. The goal is to find the safer and more…

This study tests a health behavior change program for 160 adults with both metabolic syndrome and chronic kidney disease. The program aims to reduce waist size and improve kidney function through better diet and physical activity. Participants are followed for one month after the…

This study tests a new method called PIPAC, which delivers chemotherapy as a spray directly into the abdomen for people with stomach cancer that has spread there. The goal is to see if it is safe and effective. About 30 adults aged 18 to 80 will take part, and researchers will tr…

This study tests a new way to close a macular hole (a small gap in the center of the eye's retina) in people with severe nearsightedness. Instead of using a gas bubble after surgery, doctors use a gel-like substance to hold the hole closed. The goal is to avoid the blurry vision,…

This study compares two types of radiation therapy for men with low- or intermediate-risk prostate cancer. One is a shorter, high-dose treatment (SBRT) and the other is a longer, standard treatment (IMRT). The goal is to see which one better maintains quality of life and controls…

This study tests a 10-session acceptance-based therapy designed to help people recently diagnosed with psychosis stick to their medication routine. Researchers will compare medication adherence and attitudes toward treatment between those who receive the therapy plus usual care a…

This study tested a new treatment for people with stage IVA nasopharyngeal cancer, a type of nose and throat cancer. The treatment combined the immunotherapy drug pembrolizumab with chemotherapy and radiation, followed by maintenance pembrolizumab for a year. The goal was to see …

This small pilot study tests a new robotic tool called the EndoR Surgical System for removing early-stage colorectal lesions. The system aims to make the procedure safer and more precise by giving surgeons better control. Six adults with superficial colorectal growths will be tre…

This study tests whether matching when you eat to your natural sleep-wake pattern (chronotype) helps reduce deep belly fat better than eating at mismatched times. About 90 inactive adults with central obesity will follow a 12-week time-restricted eating plan. Researchers will mea…

This study tests whether an artificial intelligence (AI) system can help doctors find early stomach cancer during a scope exam. About 260 people at high risk for stomach cancer will have two endoscopies: one without AI and one with AI. The goal is to see if the AI system catches …

This study tests whether an artificial intelligence (AI) system can help doctors accurately diagnose colon polyps during a colonoscopy, without needing to send them to a lab. Over 1,700 adults having a routine colonoscopy will be randomly assigned to have their polyps assessed by…

This study is testing a new, non-invasive MRI technique that can measure liver fat, fatty acid makeup, and scarring all at once during a single 14-second breath-hold. The goal is to see if this scan can accurately diagnose non-alcoholic steatohepatitis (NASH) without needing a li…

This study looks at whether a new digital scope can better tell the difference between cancerous and non-cancerous narrowings in the bile duct. Current methods often miss cancer, so doctors want to see if this tool improves accuracy. About 40 adults with bile duct narrowing will …

This study looks at whether sending HIV self-test kits to men who have sex with men on a subscription basis encourages them to test regularly. 240 participants in Hong Kong will be observed for one year, comparing periods with and without the kit delivery. The goal is to increase…

This study tests whether a vaccine designed for meningitis B can also protect against gonorrhea, a common sexually transmitted infection. Researchers will give two doses of the vaccine or a placebo to 150 men who have sex with men and are at high risk for gonorrhea. The goal is t…

This study tests a new program called Building Respectful Online Space (BROS) to help prevent cyberbullying among teenagers in Hong Kong. About 90 students aged 12 to 15 from secondary schools will take part, with some receiving the BROS program and others a healthy diet program …

This study tests whether a program of diet advice, exercise coaching, and behavior support can prevent type 2 diabetes in women who had gestational diabetes. 800 women will be followed for 3 years after giving birth. The goal is to see if this approach helps keep blood sugar leve…

This study tests whether bright light therapy can help ease depression in people with bipolar disorder who tend to be night owls. 70 adults will receive either bright light or a placebo light for six weeks alongside their usual treatment. The goal is to see if the light improves …

This study tests a smartphone app that uses an AI chatbot to deliver cognitive behavioral therapy for insomnia (CBT-I) to young people aged 18-25. The goal is to see if the chatbot makes the therapy more effective at reducing insomnia symptoms compared to the app alone. 168 parti…

This study tests whether a nurse-led community sailing program can improve resilience, self-esteem, and social functioning in school-aged children with autism. 184 children aged 7-12 will either take part in a 6-day sailing program or do crafting activities. Researchers will comp…

This study tests a fixed-dose combination pill called NEPA (netupitant and palonosetron) to prevent nausea and vomiting in 55 women with early breast cancer receiving chemotherapy with adriamycin and cyclophosphamide in Hong Kong. The goal is to see how well the drug works during…

This study tests a gentle ultrasound treatment aimed at a deep brain area (the hippocampus) to see if it can improve sleep and memory in older adults with early signs of Alzheimer's. Twenty participants aged 60-85 with mild memory issues and poor sleep will receive either real or…

This study tests a program where trained peer support workers help adults with first-episode psychosis manage their illness and work toward recovery. About 198 participants will take part over 18 months. The goal is to see if this approach improves self-care, social functioning, …

This study tests a special cooling cap worn during chemotherapy to prevent hair loss in Chinese women with breast cancer. About 25 participants will use the cap while receiving standard chemo. The goal is to see if the cap is safe and effective at reducing hair loss.

This study looks at which types of pneumococcus bacteria cause pneumonia in people admitted to Hong Kong hospitals. Researchers will use a simple urine test to identify the bacteria. The goal is to understand which strains are most common, which can help improve vaccines and trea…

This study looks at the gut bacteria of 120 adults to see if there are differences between people with and without fatty pancreas. Researchers want to find out if certain bacteria patterns can be used as a non-invasive test for the condition. Participants provide stool samples an…

This study looks at 1,600 adults in Hong Kong who have been diagnosed with asthma or COPD to find out how many actually have both conditions (called Asthma-COPD Overlap). Researchers will track their health for 3 years to see how they do and whether their treatments match current…

This study follows 31 Chinese adults with a specific genetic mutation (IVS4+919G>A) that causes Fabry disease, a condition that can damage the heart and kidneys over time. Researchers will use advanced heart scans and blood tests to track how the disease progresses, even before s…

This study enrolls 2000 women who had gestational diabetes to track their health over three years. Researchers will monitor blood sugar, blood pressure, and other factors to better understand long-term risks. The goal is to create better follow-up care programs and identify who m…

This study is creating a large biobank of health information and blood samples from 48,000 people with diabetes in Hong Kong. Researchers will analyze genes and other markers to better predict who is at risk for serious complications like kidney failure, heart disease, and stroke…

This study tests two school-based programs (WeJoy and WeHop) to see if they can improve mental health, sleep, and physical activity in primary school students after the COVID-19 pandemic. About 40 children in grades 3-5 will try the programs, and researchers will measure changes …

This study looks at 207 liver cancer patients to see if liver stiffness affects how well treatments like chemo, targeted therapy, or surgery work. Researchers will track overall survival and treatment side effects. The goal is to better predict outcomes and complications based on…

This study looks at a new way to measure liver and spleen stiffness using an ultrasound done through the stomach (EUS elastography). The goal is to see if this method can better predict serious liver problems like bleeding or fluid buildup in people with chronic liver disease. Ab…