Blood and tissue markers could forecast esophageal cancer return
NCT ID NCT07702253
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This study examines whether certain proteins and immune signals in the blood and tumor tissue can predict if esophageal squamous cell carcinoma will come back after treatment. Researchers will collect blood and biopsy samples from 120 adults at diagnosis and during early treatment. By mapping how the immune system interacts with the tumor, they aim to develop a way to identify patients at higher risk of recurrence.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could lead to a blood test that helps predict which esophageal cancer patients are at higher risk of recurrence, guiding more personalized treatment decisions.
- What could go wrong
- This is an observational study, not a treatment trial, so it will not directly improve outcomes. The findings may not translate into a reliable clinical test without further validation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Mar 2037
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with histologically confirmed esophageal squamous cell carcinoma receiving care at Prince of Wales Hospital, Hong Kong. Participants will provide tumour tissue and peripheral blood specimens collected during routine diagnostic, treatment, and follow-up procedures.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years. * Histologically confirmed ESCC * Able to provide written informed consent. * Able to comply with study procedures. Exclusion Criteria: * Withdrawal of consent. * Irreversible coagulation disorders preventing clinically indicated biopsies. * With other co-existing malignancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Surgery, Faculty of Medicine, the Chinese University of Hong Kong
Hong Kong, Hong Kong
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