Blood and tissue markers could forecast esophageal cancer return

NCT ID NCT07702253

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study examines whether certain proteins and immune signals in the blood and tumor tissue can predict if esophageal squamous cell carcinoma will come back after treatment. Researchers will collect blood and biopsy samples from 120 adults at diagnosis and during early treatment. By mapping how the immune system interacts with the tumor, they aim to develop a way to identify patients at higher risk of recurrence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could lead to a blood test that helps predict which esophageal cancer patients are at higher risk of recurrence, guiding more personalized treatment decisions.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly improve outcomes. The findings may not translate into a reliable clinical test without further validation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Surgery, Faculty of Medicine, the Chinese University of Hong Kong

    Hong Kong, Hong Kong

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