Fish allergy cure? new trial tests codfish therapy in kids

NCT ID NCT05590299

Ongoing Disease control Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving children with fish allergy small, increasing doses of codfish protein (oral immunotherapy) can help them tolerate fish without reactions. 70 children aged 2 to 10 will receive either codfish or a placebo for 12 months, then be tested for desensitisation and sustained unresponsiveness. The goal is to reduce the risk of accidental allergic reactions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: codfish protein (oral immunotherapy)
What this could lead to: If it works, this could offer a way for children with fish allergy to safely eat fish without severe reactions, reducing fear of accidental exposure.
What could go wrong: This is an early-stage trial with only 70 children, so results may not apply to everyone. Oral immunotherapy can cause allergic reactions during treatment, and long-term tolerance is not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

food allergy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FISH ALLERGY FOOD ALLERGY IN CHILDREN

Contacts and locations

Locations

Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong

Hong Kong, Hong Kong

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