Food allergy

This study tests whether giving young children (ages 0.5-3 years) a daily powder containing small amounts of 10 common allergens (like egg, milk, and peanut) can cure their food allergies. About 80 children with confirmed allergies will receive either the allergen powder or a pla…

This early-stage trial is testing whether a microneedle patch called MOON101, which delivers tiny amounts of peanut protein into the skin, is safe for people with peanut allergies. The study will enroll 40 participants, including adults, teenagers, and children. Each person will …

This expanded access program offers continued treatment with dupilumab to adults who have severe IgE-mediated food allergies and were previously treated with linvoseltamab and dupilumab in an earlier study. The goal is to provide ongoing access to the medication for those who com…

This Phase 2 trial tests whether adding tezepelumab (a biologic drug) to peanut oral immunotherapy (OIT) helps people with peanut allergy tolerate more peanut without symptoms. 62 participants aged 12 to 55 will first receive tezepelumab or placebo alone, then both groups undergo…

This study tests a new injection called UKK-0018 for people with peanut allergies. The goal is to train the immune system to handle peanut exposure without a severe reaction. The trial involves 40 adults aged 18-55 and will first check safety, then see if it helps increase the am…

This study is testing a skin patch called Viaskin that delivers a tiny amount of peanut protein to help 1-3 year olds with peanut allergy. The goal is to see if the patch is safe over 6 months. About 480 children will wear the patch or a placebo daily. This is a phase 3 trial, me…

This study tests whether omalizumab injections, given every two weeks for 24 weeks, can help people aged 1 to 55 with high IgE levels tolerate more of their trigger foods. Participants who respond may then try adding the food to their diet with extra injections. The goal is to se…

This study tests a new drug called RPT904 in about 100 people aged 12 to 55 who are allergic to foods like peanut, milk, egg, cashew, or walnut. RPT904 is a long-acting antibody that blocks allergic reactions and may only need to be given every 8 to 12 weeks. The goal is to see i…

This study tests a bone marrow transplant from a family donor for children under 21 with severe non-cancer blood disorders like sickle cell disease, bone marrow failure, or immune problems. The goal is to see if the transplant can replace the diseased cells with healthy donor cel…

This study tests whether giving children with peanut allergy small, increasing amounts of peanut protein (oral immunotherapy) can help them tolerate more peanut without a reaction. It compares this approach to the standard care of strictly avoiding peanuts. The goal is to see if …

This study tests whether eating small, increasing amounts of boiled cashew flour can help children with cashew allergy tolerate the nut without severe reactions. 75 children aged 2 to 17 will receive either boiled cashew flour or a placebo over time. The goal is to see if this ap…

This study tests modified oral immunotherapy (OIT) protocols for peanut, milk, and egg allergies in 360 participants. The goal is to see if using lower doses or processed allergens can reduce allergic reactions during treatment while still helping people become desensitized to th…

This study tests whether gradually introducing cow's milk in less-heated forms over 12 months helps children with milk allergy develop full tolerance faster than just eating well-cooked milk. About 90 children aged 1-18 who already tolerate heated milk will be split into groups: …

This early-stage trial tests a drug called MY006, given as a shot under the skin, to see if it can prevent severe allergic reactions from accidental peanut intake. The study involves 48 healthy volunteers and people with peanut allergies, who will receive either the drug or a pla…

This study tests a new daily oral treatment called ENP-501 for peanut allergy. It involves 68 healthy volunteers and people with a known peanut allergy. The treatment is given under the tongue daily for up to 52 weeks to see if it is safe and helps people tolerate peanut protein …

This study compares two ways of giving oral immunotherapy to children aged 6–16 with milk or egg allergy. One method uses daily increasing doses over a week ('rush'), while the other uses doses every two weeks ('conventional'). The goal is to see which is safer and more effective…

This study tests if higher doses of omalizumab (Xolair) can help people with food allergies tolerate more of their trigger foods. Thirty participants with allergies to peanut, cashew, walnut, egg, or milk will receive either 5 mg/kg or 15 mg/kg of omalizumab for 16 weeks. The goa…

This program provides continued access to the Viaskin Peanut skin patch for children aged 2 and older with peanut allergy who previously completed a DBV712 study. The patch delivers a small amount of peanut protein through the skin each day to help desensitize the immune system. …

This study is testing a new blood test (called BÜHLMANN BAT) to see if it can help diagnose allergies to peanuts, insect venom, dust mites, hazelnut, and cat dander. About 60 people aged 1.5 years and older who are already being checked for allergies will give one extra tube of b…

This study looks at better ways to diagnose allergies to common legumes like peas, lentils, chickpeas, and green beans. About 100 people with suspected legume allergies will take skin prick tests, blood tests for specific IgE antibodies, and a newer component test. Results will b…

This study tests whether giving parents educational materials and in-person feeding support helps them introduce allergenic foods like eggs to infants early and keep them in the diet. Researchers will compare two groups of 92 infants to see which approach leads to earlier and mor…

This study is testing a serious video game designed to improve emotional well-being in teenagers aged 12 to 16, both with and without chronic conditions like type 1 diabetes, asthma, and allergies. The game uses artificial intelligence to personalize activities that build coping …

This study looks at the safety of a nasal spray called neffy compared to a standard epinephrine shot for treating allergic reactions. It involves 600 people aged 4 and older who have an allergic reaction during a food challenge or allergy shot session. The goal is to see if the s…

This study is testing whether a new formula made from hydrolyzed rice proteins is safe for infants and young children (1–36 months) with IgE-mediated cow's milk allergy. In a double-blind test, children will receive either the rice formula or a placebo, then be monitored for alle…

This study looks at whether giving steroids along with antihistamines helps children recover faster from allergic reactions to food. About 160 children with food allergies will participate during a scheduled food challenge at the clinic. Half will receive antihistamines alone, an…

This study tests a special infant formula designed for babies with cow's milk protein allergy. The formula includes added prebiotics, probiotics, and a human milk oligosaccharide to help ease allergy symptoms. About 41 infants under 10 months old will use the formula for 4 weeks,…

This study aims to learn more about how diseases related to blood clots, the immune system, and blood vessels start and change over time. Researchers will enroll up to 1,000 people aged 5 and older, including those with these conditions, their healthy relatives, and healthy volun…

This study looks at the causes and effects of food allergies and related conditions like eczema and eosinophilic esophagitis. Researchers will collect blood, skin, and genetic samples from up to 1,800 people over many years. The goal is to find biomarkers and pathways that explai…

This study looks at 200 people aged 3–21 with eczema and high IgE levels who may have milk or peanut allergies. Researchers will use oral food challenges to find better ways to predict true allergies. The goal is to make allergy tests more accurate and reduce unnecessary food res…

This study looks for better ways to detect lung inflammation and infections early in people who have received a stem cell transplant from a donor. About 40 participants aged 5 to 70 will get regular lung scans, breathing tests, blood draws, and a procedure where a tube collects f…

This study is testing a tool called B-COMPASS that uses a 22-question survey to predict whether people will follow their prescribed treatments. Researchers will enroll 3100 adults with cardiovascular, endocrine, immune, nerve, cancer, or rare diseases across Europe. The goal is t…

Stanford University is recruiting 2,500 people with possible allergies to improve how allergies are diagnosed. Researchers will study skin test responses and look at genetic and immune system factors. This study does not test any new treatment, but aims to deepen knowledge of all…

This study is testing a new method to measure allergy-related substances (IgE) in blood and urine. Researchers want to see if this new technique works as well as current tests. About 1,376 children and adults with allergies will provide blood and urine samples during routine visi…

This study looks at children aged 4 to 10 with mild to moderate cow's milk or egg allergies. Researchers want to find biological markers that predict whether a child will naturally outgrow their allergy or benefit from oral immunotherapy (OIT). The goal is to help families and do…

This study is collecting blood, urine, and breath samples from 280 adults—including those with metal allergies and healthy volunteers—to see if exposure to heavy metals and pollutants leaves distinct biological markers. Researchers will compare levels of metals, lung function, an…

This study is creating a large registry of 800 people receiving biologic medications for immune conditions like autoimmune diseases and primary immune deficiencies. Researchers will collect blood samples and health data to better understand how these treatments work and who respo…

This study looks at how indoor air and dust pollutants in classrooms impact children's allergies and lung function. Researchers will monitor 100 children, comparing those with allergies to those without, using questionnaires, allergy tests, and breathing tests. The goal is to ide…

This long-term study follows 1,000 people with eczema and related allergies, plus healthy volunteers, to see what factors help the disease go into remission. Researchers will collect medical and lifestyle data to find patterns and possible biomarkers. The goal is to better unders…

This study aims to find the genetic causes behind certain allergic and immune system disorders. Researchers will collect blood, saliva, and tissue samples from up to 10,000 people of all ages, along with some family members. No treatments are given; the goal is simply to learn mo…

This study looks at children and young people who completed an 18-month oral immunotherapy (OIT) treatment for peanut, egg, or milk allergy 5 to 15 years ago. Researchers want to compare quality of life between those whose allergies went into remission and those whose did not. Pa…

This study looks at whether frozen or stored foods can be used for allergy skin prick tests instead of fresh foods. Researchers will test 100 adults with known food allergies using both fresh and stored foods to see if the results match. The goal is to make allergy testing easier…

This study aims to collect blood, nasal fluid, skin cells, urine, and medical data from 10,000 people aged 3 to 100 with allergies, asthma, eczema, or sinus issues. Participants will have up to 3 years of follow-up visits and questionnaires. The goal is to create a large reposito…

This study screens up to 1,000 people with possible food allergies to see if they qualify for future clinical trials at Stanford. Participants undergo food challenges and skin tests to confirm their allergies. The goal is to build a pool of diagnosed individuals ready for upcomin…

This study collects blood and skin samples from 200 people with eczema, food allergies, or neither. Researchers will analyze these samples to find shared genetic or biochemical signals. The goal is to better understand how these conditions are connected, which could lead to bette…

This study will test 2,000 allergy patients at Montpellier University Hospital for sensitivity to six foods containing gibberellin-related proteins (GRPs): peach, apple, sesame, carrot, lemon, and orange. Using skin prick tests with raw foods, researchers aim to find out how comm…

This study is looking at how eosinophils (a type of white blood cell) grow, move, and cause inflammation in people with eosinophilic gastrointestinal disease, other eosinophilic inflammatory conditions, or food allergies. Researchers will also study healthy volunteers and family …