Can a shot help people with high IgE eat more foods safely?
NCT ID NCT06934200
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether omalizumab injections, given every two weeks for 24 weeks, can help people aged 1 to 55 with high IgE levels tolerate more of their trigger foods. Participants who respond may then try adding the food to their diet with extra injections. The goal is to see if this approach is safe and effective for those who don't qualify for standard dosing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- omalizumab injections
- What this could lead to
- If successful, this could offer a new treatment option for people with food allergies who have high IgE levels, potentially allowing them to safely eat small amounts of trigger foods.
- What could go wrong
- This is a small, early-phase trial with only 32 participants. The treatment may not work for everyone, and there is a risk of allergic reactions during food challenges.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins
RECRUITINGBaltimore, Maryland, 21287, United States
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