Can a shot help people with high IgE eat more foods safely?

NCT ID NCT06934200

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether omalizumab injections, given every two weeks for 24 weeks, can help people aged 1 to 55 with high IgE levels tolerate more of their trigger foods. Participants who respond may then try adding the food to their diet with extra injections. The goal is to see if this approach is safe and effective for those who don't qualify for standard dosing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

omalizumab injections

What this could lead to

If successful, this could offer a new treatment option for people with food allergies who have high IgE levels, potentially allowing them to safely eat small amounts of trigger foods.

What could go wrong

This is a small, early-phase trial with only 32 participants. The treatment may not work for everyone, and there is a risk of allergic reactions during food challenges.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

food allergy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••