Scientists hunt for biomarkers linking everyday toxins to allergies and illness

NCT ID NCT06529913

Recruiting now Knowledge-focused Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is collecting blood, urine, and breath samples from 280 adults—including those with metal allergies and healthy volunteers—to see if exposure to heavy metals and pollutants leaves distinct biological markers. Researchers will compare levels of metals, lung function, and signs of inflammation between groups. The goal is to better understand how environmental exposures may contribute to disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify biomarkers that predict who is at risk for diseases caused by heavy metals and pollutants.
What could go wrong: This is an early observational study, not a treatment trial. It may not find clear differences between groups, and results may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

allergic contact dermatitis atopic eczema contact dermatitis due to nickel digestive system disorder Eczema Environmental Illness food allergy Risk Reduction Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLERGIC CONTACT DERMATITIS ALUMINUM ALLERGY CHROMIUM; ECZEMA ENVIRONMENT RELATED DISEASE ENVIRONMENTAL EXPOSURE ENVIRONMENTAL ILLNESS FOOD ALLERGY FUNCTIONAL GASTROINTESTINAL DISORDERS METAL ALLERGY NICKEL SENSITIVITY NICKEL; ECZEMA OXIDATIVE STRESS POLLUTION RELATED RESPIRATORY DISORDER POLLUTION; EXPOSURE RESPIRATORY INJURY RISK REDUCTION

Contacts and locations

Locations

Fondazione Policlinico Universitario A. Gemelli IRCCS
RECRUITING

Roma, 00168, Italy
Università di Bologna
NOT_YET_RECRUITING

Bologna, 40126, Italy

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