RISK REDUCTION

This study will enroll 500,000 people with high myopia and cataracts to develop an artificial intelligence model that helps doctors calculate the correct lens power and grade cataracts more accurately. The goal is to improve vision outcomes and reduce complications after surgery.…

This study is testing a digital platform called DELPHI that uses a wearable fitness tracker and smartphone app to give personalized lifestyle tips on exercise, sleep, diet, and stress. Researchers will enroll 200 healthy adults in southern Italy and randomly assign them to use ei…

This study tests whether a coach-guided, personalized risk communication tool can help prevent major depression in adults at high risk. Researchers will recruit 1,000 participants across Canada and randomly assign them to receive either the coach-guided tool or standard depressio…

This international study aims to understand why colorectal cancer is becoming more common in people under 50. Researchers will compare the diet, lifestyle, and medical history of 2,300 participants—half with early-onset colorectal cancer and half healthy volunteers. The goal is t…

This study gives healthy adults the licensed oral typhoid vaccine (Vivotif) and collects blood, saliva, and stool samples over up to eight years. Researchers want to learn how the vaccine triggers protective immune responses, which could help design better vaccines for typhoid an…

This study is collecting blood, urine, and breath samples from 280 adults—including those with metal allergies and healthy volunteers—to see if exposure to heavy metals and pollutants leaves distinct biological markers. Researchers will compare levels of metals, lung function, an…