Food allergy

This study looked at whether the HPV vaccine works in girls aged 9 to 17 who are taking medicines that weaken their immune system, such as after an organ transplant or for diseases like lupus. The goal was to see if their bodies produce enough antibodies to protect against HPV. T…

This study tested a drug called remibrutinib in 76 adults with peanut allergy. Participants took one of three doses or a placebo daily for one month. The main goal was to see if the drug helped them eat more peanut protein without having an allergic reaction. Results showed some …

This phase 2 study tested the drug Xolair (omalizumab) in 11 people with peanut allergies who had already completed a previous trial. The goal was to see if the drug could reduce serious allergic reactions. Participants received regular injections of Xolair and reported any peanu…

This study tested whether adding the drugs omalizumab (Xolair) or dupilumab (Dupixent) to oral immunotherapy (OIT) helps people with multiple food allergies tolerate more allergens. 130 participants aged 4 to 55 with allergies to peanut plus one or two other foods were enrolled. …

This study tested a daily tablet placed under the tongue (SLIT) containing peanut protein to help people with peanut allergy tolerate small amounts of peanut. The trial included 209 adults, teens, and children ages 4 to 65. Researchers measured how many participants could safely …

This study tested a home-based, dietitian-led 'egg ladder' for infants newly diagnosed with egg allergy. Over 12 months, babies gradually ate more cooked egg, starting with baked goods. The goal was to see if this approach is safe and feasible. 109 infants participated, and resea…

This study followed 250 children who received oral immunotherapy (OIT) for severe milk allergy to see how well it works over time. Researchers measured how much milk participants could drink and how their quality of life improved. The goal is to understand the long-term benefits …

This early-stage trial tested whether taking fecal transplants in capsules could help people with peanut allergy tolerate more peanut without a reaction. Fifteen adults aged 18 to 40 received the treatment, and researchers checked for side effects and changes in peanut tolerance.…

This phase 2 study tested whether the drug omalizumab (Xolair) can make oral immunotherapy safer for people with multiple food allergies. Sixty participants aged 2 to 25 received omalizumab before gradually increasing doses of their problem foods. The goal was to see if this appr…

This small pilot study tested whether adding a prebiotic fiber (a type of plant fiber found in grocery stores) to peanut oral immunotherapy could help children aged 4 to 17 with peanut allergy tolerate more peanut protein with fewer side effects. Twenty children participated, and…

This study tested a low-dose oral immunotherapy (OIT) in children aged 18-36 months with allergies to two nuts. Over 18 months, one group received daily tiny doses of the nuts they were allergic to, while the other group avoided them completely. The goal was to see if more childr…

This study tested a new supplement in 30 children with food allergies who were already avoiding certain foods. The goal was to see if the supplement could improve their growth, vitamin D and DHA levels, and immune system balance. The supplement is not a cure but aims to help chil…

This study tested whether giving children with peanut allergy a daily dose of peanut protein (either 150 mg or 300 mg) could help them tolerate more peanuts over time. 44 children participated, and researchers measured how much peanut protein they could safely eat after treatment…

This early-stage trial tested a single injection of a new drug called IGNX001 in 32 adults and teens with peanut allergies. The main goal was to check safety and how the body processes the drug. Participants received either the drug or a placebo, and researchers monitored for sid…

This completed trial tested whether eating specially prepared pancakes daily could help children with egg allergy tolerate eggs. 23 children participated, starting with small doses in the hospital and continuing at home. The goal was to see if they could eat a full serving of coo…

This study tested whether omalizumab (Xolair), an allergy drug, helps people with peanut and at least two other food allergies eat those foods without severe reactions. Over 470 participants aged 1 to 55 received omalizumab or a placebo, and some also got oral immunotherapy. The …

This study tested a blood test called the Basophil Activation Test (BAT) to see if it can accurately diagnose peanut and egg allergies in children. Currently, the gold standard is an oral food challenge, which can cause severe allergic reactions. The researchers compared BAT resu…

This study compared three FDA-cleared allergy skin test devices (AllerTest-10, Lincoln Multi-Test II, and Greer Skintestor OMNI) in 30 adults to see which is most accurate and least painful. Participants received histamine and glycerin controls on their skin, and researchers meas…

This study looked at whether a blood test called the basophil activation test (BAT) can accurately diagnose food allergies in children, potentially replacing the need for oral food challenges (OFCs). Researchers tested 116 children aged 0-18 who were already scheduled for an OFC.…

This study tested a digital tool called iREACH that helps pediatricians follow national guidelines for introducing peanuts to infants. The tool provides reminders and education during checkups at 4, 6, 9, and 12 months. Researchers measured how well doctors followed the guideline…

This study tested whether giving tree nuts early to infants with peanut allergy could prevent them from developing tree nut allergies. 212 babies aged 4-11 months were split into two groups: one had a supervised hospital challenge with four tree nuts followed by home introduction…

This study looked at whether a therapeutic education program can improve quality of life for children aged 8 to 12 with IgE-mediated food allergies, as well as their families. 46 children and their families took part. The program focused on teaching them how to manage allergies a…

This study looked at 107 people with severe food or insect allergies to measure the distance from skin to muscle in their thighs. The goal was to see if the needles on common epinephrine auto-injectors (like EpiPen) are long enough to deliver the medicine into the muscle, as reco…

This study tested a new drug called l-dipivefrin (IN-001) given under the tongue as a spray or drops, compared to standard epinephrine injections, in 32 healthy adults. The goal was to see how the body absorbs the drug and its safety. It is an early-stage study to gather informat…

This study looked at 185 children aged 0-6 to compare the nutrition and growth of those with food allergies to healthy children. Researchers measured things like arm circumference and height to see if allergies affect development. The goal was to better understand how food allerg…

This completed study looked at levels of a specific antibody (IgG4) to cow's milk and egg in 135 children, both with and without allergies. Researchers wanted to see if these levels could help tell which children have outgrown their allergy. The study involved a single blood draw…

This study looked at 96 adults with house dust mite allergy to see if they also react to edible insects like crickets or mealworms. Participants had skin prick tests and their allergy history was reviewed. The goal was to understand patterns of insect sensitization, especially in…

This completed pilot study collected health and nutrition information from 300 healthy adults living in Northern California. Participants completed an online survey about their stress levels, nut consumption, and bowel habits. The goal was to test and improve study procedures for…

This completed study looked at 147 French children with confirmed peanut or tree nut allergies to see how often they accidentally have allergic reactions in everyday life. Researchers also recorded how severe those reactions were and what factors might increase risk. The goal is …

This study collected blood, saliva, stool, urine, and skin samples from 19 people with unknown or poorly understood immune system problems. The goal was to learn how different parts of the immune system work together. No treatments or drugs were tested. Participants were followed…