Tiny doses, big hope: new therapy may help kids outgrow nut allergies

NCT ID NCT05049512

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a low-dose oral immunotherapy (OIT) in children aged 18-36 months with allergies to two nuts. Over 18 months, one group received daily tiny doses of the nuts they were allergic to, while the other group avoided them completely. The goal was to see if more children in the OIT group could safely eat the nuts after stopping treatment, compared to those who simply avoided nuts. The study is small and early-stage, so results are not yet conclusive.

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Conditions

The condition(s) this trial relates to.

food allergy Nut Hypersensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia