Fiber fix for peanut allergy? small study tests prebiotic boost to OIT
NCT ID NCT05138757
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small pilot study tested whether adding a prebiotic fiber (a type of plant fiber found in grocery stores) to peanut oral immunotherapy could help children aged 4 to 17 with peanut allergy tolerate more peanut protein with fewer side effects. Twenty children participated, and the study looked at safety and how many could eat at least 2044 mg of peanut protein with only mild symptoms after 12 months. The results are preliminary and need larger studies to confirm.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- prebiotic fiber
- What this could lead to
- If it works, this could point toward a way to make peanut oral immunotherapy safer and more effective by adding a simple dietary fiber.
- What could go wrong
- This is a very small pilot study with only 20 participants, so results may not apply broadly. The prebiotic is not FDA-approved for this use, and side effects like stomach issues are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Comer Children's Hospital
Chicago, Illinois, 60637, United States
-
University of Chicago- Department of Pediatrics
Hyde Park, Illinois, 60637, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can allergy drugs help kids tolerate peanut and more?
- Peanut allergy patch enters human safety trials
- Could supermarket peanuts and milk cure food allergies? new study investigates.
- New daily oral treatment aims to tame peanut allergy