Fiber fix for peanut allergy? small study tests prebiotic boost to OIT
NCT ID NCT05138757
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small pilot study tested whether adding a prebiotic fiber (a type of plant fiber found in grocery stores) to peanut oral immunotherapy could help children aged 4 to 17 with peanut allergy tolerate more peanut protein with fewer side effects. Twenty children participated, and the study looked at safety and how many could eat at least 2044 mg of peanut protein with only mild symptoms after 12 months. The results are preliminary and need larger studies to confirm.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
prebiotic fiber
What this could lead to
If it works, this could point toward a way to make peanut oral immunotherapy safer and more effective by adding a simple dietary fiber.
What could go wrong
This is a very small pilot study with only 20 participants, so results may not apply broadly. The prebiotic is not FDA-approved for this use, and side effects like stomach issues are possible.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Comer Children's Hospital
Chicago, Illinois, 60637, United States
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University of Chicago- Department of Pediatrics
Hyde Park, Illinois, 60637, United States