Peanut allergy cure in sight? trial tests tolerance in teens

NCT ID NCT02046083

First seen Jul 31, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This trial tests whether giving teenagers with peanut allergy gradually increasing amounts of peanut protein can help them build tolerance. The goal is to see if they can safely eat a cumulative dose of 2 grams of peanut without an allergic reaction. The study also looks at whether a longer maintenance phase can improve the chances of lasting tolerance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
arachid (peanut protein)
What this could lead to
If successful, this approach could help teenagers with peanut allergy safely eat peanuts, potentially reducing the risk of severe reactions from accidental exposure.
What could go wrong
This is an early-stage trial with a small number of participants, and results may not apply to all. There is a risk of allergic reactions during the dose-escalation process.

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Conditions

The condition(s) this trial relates to.

Peanut Hypersensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

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