New antibody aims to neutralize allergies by clearing IgE

NCT ID NCT07701954

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This early-stage trial tests an experimental antibody drug called LCA-0061, designed to target and remove immunoglobulin E (IgE), a key driver of allergic reactions. The study first evaluates safety and tolerability in healthy people with elevated IgE levels, then in people with peanut allergy. Researchers are looking at how the drug moves through the body and whether it triggers an immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an antibody-based drug called LCA-0061 that targets and clears immunoglobulin E (IgE)
What this could lead to
If successful, this could lead to a new treatment for peanut allergy and other allergic conditions by lowering IgE levels.
What could go wrong
This is an early Phase 1 trial focused on safety, so it is too soon to know if the drug will effectively treat allergies. Side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CAN001

    RECRUITING

    Mississauga, Ontario, L4W 1N2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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