Can a higher dose of xolair beat food allergies?

NCT ID NCT06943534

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests if higher doses of omalizumab (Xolair) can help people with food allergies tolerate more of their trigger foods. Thirty participants with allergies to peanut, cashew, walnut, egg, or milk will receive either 5 mg/kg or 15 mg/kg of omalizumab for 16 weeks. The goal is to see if they can then eat at least 600 mg of the allergen without a reaction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

omalizumab (Xolair)

What this could lead to

If successful, this could lead to a more effective dosing strategy for omalizumab, helping people with food allergies tolerate larger amounts of trigger foods without severe reactions.

What could go wrong

This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. Higher doses may also increase side effects or fail to improve tolerance.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

allergic disease food allergy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Email: •••••@•••••

  • University of Texas Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Email: •••••@•••••