Massive study aims to unravel mysteries of eosinophilic diseases
NCT ID NCT00267501
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is looking at how eosinophils (a type of white blood cell) grow, move, and cause inflammation in people with eosinophilic gastrointestinal disease, other eosinophilic inflammatory conditions, or food allergies. Researchers will also study healthy volunteers and family members for comparison. The goal is to better understand these conditions, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this research could lead to a deeper understanding of eosinophilic diseases and food allergies, potentially pointing toward new treatments.
- What could go wrong
- This is an observational study, not a treatment trial. It is designed to gather knowledge, not to test a therapy, so direct patient benefits are unlikely in the near term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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May 2005
- Expected to finish
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Jan 2050
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with eosinophilic disorders and patients without eosinophilic disorders to serve as normal controls
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Signed informed consent obtained from the patient or parent/guardian. Assent will be obtained from all minors 11 years of age and older. * Carrying a diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy OR family member, or normal control
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229-3039, United States
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