Can a common antibiotic prevent STIs? new study tests two dosing strategies

NCT ID NCT06188442

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether taking doxycycline before potential exposure to STIs works better than taking it after exposure. 300 men who have sex with men will be randomly assigned to one of two groups and followed for 2 years. The goal is to see which approach better prevents chlamydia, gonorrhea, and syphilis, and whether both are safe and acceptable.

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Conditions

The condition(s) this trial relates to.

bacterial sexually transmitted disease chlamydia infectious disease Homosexuality sexually transmitted disease chlamydia trachomatis infectious disease prevention target gonorrhea prevention target syphilis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Stanley Ho Centre for Emerging Infectious Diseases

    Shatin, Hong Kong