SYPHILIS

This study aims to reduce sexually transmitted infections like chlamydia and gonorrhea among Black youth aged 15-26 in New Orleans. Participants receive free testing for four STIs and, if positive, get counseling and no-cost treatment options for themselves and their partners. Th…

This study compares two antibiotics for treating early syphilis: an oral pill (cefixime) versus a standard shot (penicillin). About 400 adults with early-stage syphilis, including those with well-controlled HIV, will take part. The goal is to see if the pill works as well as the …

This study offers routine and rapid syphilis testing to pregnant women who come to the emergency room or obstetrical triage without having had prenatal care or a syphilis test during their pregnancy. The goal is to increase the number of women who get full treatment and ensure bo…

This study evaluates a new point-of-care device called MagIA H3S that can test for HIV, hepatitis B, hepatitis C, and syphilis from a single blood sample. Researchers will enroll about 2,950 people in Ivory Coast and Kenya to see how accurate the device is compared to standard la…

This study aims to see if newer, more precise lab tests can detect syphilis in pregnant women and their newborns better than current standard methods. About 924 participants will provide samples shortly after birth. The goal is to improve diagnosis and prevent long-term health pr…

This study is checking if a new rapid test, using just a drop of blood from a fingerstick, can accurately diagnose syphilis. About 1,300 people visiting a sexual health clinic in Ottawa will take part. The goal is to see if this quick test works as well as the standard lab test, …

This study tests whether taking the antibiotic doxycycline can prevent bacterial sexually transmitted infections (STIs) like chlamydia, gonorrhea, and syphilis in adolescent and young adult females aged 13-29 who are at high risk. About 760 participants will be randomly assigned …

This study tests whether taking the antibiotic doxycycline shortly after sex (called doxy-PEP) can prevent bacterial STIs like syphilis, gonorrhea, and chlamydia. It involves 200 sexual and gender minorities in Rio de Janeiro who are living with HIV or taking PrEP. Participants c…

This study looks at how syphilis bacteria spread in women and men who have sex with women only, even when there are no visible sores. Researchers will collect swabs and blood samples from 480 participants to see if the bacteria are alive and can be passed to others. The goal is t…