Antibiotic shield: doxycycline may stop STIs in young women
NCT ID NCT06738407
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking the antibiotic doxycycline can prevent bacterial sexually transmitted infections (STIs) like chlamydia, gonorrhea, and syphilis in adolescent and young adult females. About 760 participants aged 13-29 who have had an STI in the past year and recent condomless sex will take doxycycline or receive standard care. The goal is to see if this approach reduces new infections and is acceptable for wider use.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77030, United States
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Chapel Hill
NOT_YET_RECRUITINGChapel Hill, North Carolina, 27599, United States
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Children's National Medical Center
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Harlem Prevention Center
NOT_YET_RECRUITINGNew York, New York, 10027, United States
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Johns Hopkins University
NOT_YET_RECRUITINGBaltimore, Maryland, 21287, United States
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Penn Prevention
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Ponce de Leon
NOT_YET_RECRUITINGAtlanta, Georgia, 30303, United States
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San Francisco Department of Public Health
RECRUITINGSan Francisco, California, 94102, United States
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38015, United States
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Tulane University
NOT_YET_RECRUITINGNew Orleans, Louisiana, 70112, United States
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UCLA Care
NOT_YET_RECRUITINGLos Angeles, California, 90095, United States
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University Illinois Chicago
RECRUITINGChicago, Illinois, 60612, United States
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University of Florida
RECRUITINGTampa, Florida, 33612, United States
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Other studies related to the condition(s) this trial covers.
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