Could a pill replace the shot for syphilis?
NCT ID NCT04958122
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two antibiotics for treating early syphilis: a single penicillin shot (standard care) versus a 14-day course of cefixime pills. Researchers want to see if the pill works just as well. The study includes 400 adults with early syphilis, including those with well-controlled HIV.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Southern California
RECRUITINGLos Angeles, California, 90032, United States
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