Could new DNA tests spot syphilis in newborns faster?

NCT ID NCT06082453

Recruiting now Diagnosis Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing two new molecular tests (qPCR and TMA) to detect syphilis in pregnant women and their newborns. Researchers will compare these tests to current CDC guidelines to see if they are more accurate. The goal is to improve diagnosis and prevent congenital syphilis, which can cause serious health issues in babies. About 924 participants will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: qPCR and TMA diagnostic tests
What this could lead to: If successful, these new tests could provide faster, more accurate syphilis diagnosis for mothers and babies, helping prevent serious health problems.
What could go wrong: This is an early-stage diagnostic study, not a treatment trial. The tests may not prove more accurate than current guidelines, and results won't be used for patient care during the study.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SYPHILIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

syphilis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYPHILIS

Contacts and locations

Locations

Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Christus Health
RECRUITING

Houston, Texas, 78130, United States
Johns Hopkins University
RECRUITING

Baltimore, Maryland, 21205, United States
Kennedy Krieger Institute
RECRUITING

Baltimore, Maryland, 21205, United States
Nationwide Children's Hospital
RECRUITING

Columbus, Ohio, 43205, United States
Texas Children's Hospital
RECRUITING

Houston, Texas, 77030, United States
The University of Texas Health Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States
University of California, Los Angeles
RECRUITING

Los Angeles, California, 90095, United States
University of Southern California
RECRUITING

Los Angeles, California, 90007, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.