One Breath-Hold MRI could replace liver biopsies for NASH
NCT ID NCT05384652
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new MRI technique that measures liver fat, fibrosis, and inflammation in a single 14-second breath-hold, without needles or contrast dye. Researchers will scan 120 people with fatty liver disease (60 with simple steatosis and 60 with NASH) and compare results to liver biopsies. If accurate, this could offer a non-invasive way to diagnose NASH and track liver health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MRI scan (no drug or device)
What this could lead to
If successful, this could provide a fast, needle-free way to diagnose NASH and monitor liver health without a biopsy.
What could go wrong
This is an early diagnostic study, not a treatment trial. The new MRI method may not be accurate enough to replace biopsies, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Chinese University of Hong Kong, Prince of Wale Hospital
Hong Kong, Shatin, Hong Kong