Can a promising NAFLD drug safely mix with other medicines? a trial seeks answers
NCT ID NCT07726368
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial investigates whether ECC4703, a potential new treatment for non-alcoholic fatty liver disease (NAFLD), changes how the body processes two other drugs: sulfasalazine and pitavastatin. Healthy adults aged 18 to 65 will take these drugs alone and then with ECC4703 to measure any differences in drug levels. The goal is to understand possible drug interactions early, ensuring safety for future patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ECC4703, sulfasalazine, and pitavastatin
- What this could lead to
- If successful, this trial could help determine safe dosing of ECC4703 with common medications, supporting its development as a treatment for non-alcoholic fatty liver disease.
- What could go wrong
- This is an early-phase drug interaction study in healthy volunteers, not patients. Results may not predict real-world effects in people with NAFLD, and ECC4703 could still fail in later trials.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Nucleus Network Pty Ltd
Melbourne, Victoria, 3004, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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