Laxative before dialysis catheter insertion may reduce blockages

NCT ID NCT07351357

Not yet recruiting Disease control Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking a laxative (bisacodyl) for two days before getting a peritoneal dialysis catheter can prevent blockages. About 398 adults needing dialysis will be randomly assigned to receive the laxative or usual care. The goal is to see if this simple step reduces the need for procedures to fix catheter drainage problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bisacodyl 5 mg (a laxative)
What this could lead to: If it works, this could provide a simple, low-cost way to reduce catheter blockages in people starting peritoneal dialysis.
What could go wrong: This is a Phase 4 trial, but it's still early and results may not apply to all patients. The laxative could cause side effects like diarrhea or cramping.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERITONEAL DIALYSIS RENAL FAILURE CHRONIC REQUIRING DIALYSIS

Contacts and locations

Locations

Caritas Medical Centre

Sham Shui Po, Kowloon, SAR, Hong Kong
Prince of Wales Hospital

Shatin, NT, SAR, Hong Kong
Prince of Wales Hospital

Shatin, Hong Kong
Princess Margaret Hospital

Kwai Chung, Kowloon, SAR, Hong Kong
Queen Elizabeth Hospital

Yau Ma Tei, NT, SAR, Hong Kong
Tseung Kwan O Hospital

Tseung Kwan O, NT, SAR, Hong Kong

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