New dialysis solution may delay need for full treatment in kidney patients
NCT ID NCT05721404
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This trial investigates whether using icodextrin, a special dialysis solution, can help people on peritoneal dialysis (a type of home dialysis for kidney failure) stay on a lower-dose regimen for longer. Participants are randomly assigned to receive either icodextrin or a standard sugar-based solution when they show signs of fluid overload. The goal is to see if icodextrin delays the need to switch to full-dose dialysis and improves outcomes like infection rates and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Icodextrin peritoneal dialysis solution
- What this could lead to
- If it works, this could help people on peritoneal dialysis maintain a lower treatment burden for longer, with less glucose exposure and potentially fewer complications.
- What could go wrong
- This is a single-center Phase 4 trial with 194 participants, so results may not apply broadly. The benefit may be modest, and icodextrin can cause side effects like skin reactions or sterile peritonitis.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital, Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, 510080, China
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