Pumpkin seed oil may fight inflammation in kidney patients — a trial puts it to the test

NCT ID NCT06314243

Completed Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial investigates whether daily pumpkin seed oil supplements can reduce inflammation, oxidative stress, and unhealthy blood fats in people undergoing hemodialysis. Researchers will compare a group taking the oil with a group that does not, measuring markers like interleukin-6 and malondialdehyde. The goal is to see if this natural supplement could improve health outcomes for patients with kidney failure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pumpkin seed oil dietary supplement
What this could lead to: If it works, this could point toward a simple, natural supplement to help manage inflammation and heart-disease risk in dialysis patients.
What could go wrong: This is a small, early-stage trial with only 56 participants. The supplement may not produce meaningful improvements, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMODIALYSIS PATIENTS

Contacts and locations

Locations

Adult Nephrology and Dialysis Unit, Ain Shams University Hospital, Cairo, Egypt.

Cairo, 11766, Egypt

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