Kidney dialysis patients: new study tests blood thinner safety

NCT ID NCT04006093

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how a single 5 mg dose of the blood thinner apixaban is processed in people with end-stage kidney disease who are on peritoneal dialysis, compared to people with normal kidney function. Researchers measured drug levels in the blood over time. The goal is to understand if dosing adjustments are needed for this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

apixaban (a blood thinner)

What this could lead to

If successful, this could help doctors determine safe and effective dosing of apixaban for people on peritoneal dialysis.

What could go wrong

This is a small, early-phase study with only 24 participants, so results may not apply to everyone. It looks at drug levels, not clinical outcomes like bleeding or clotting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Caen

    Caen, 14000, France