HIV drug switch study aims to uncover hidden resistance risks

NCT ID NCT07643948

Recruiting now Knowledge-focused Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 420 adults with HIV whose virus is fully suppressed by medication. Researchers want to see if switching to a different HIV drug regimen causes hidden drug resistance to appear. They will compare people who switch drugs with those who stay on their current treatment, including some with very low levels of virus. The goal is to learn how to make treatment switches safer and more effective over the long term.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors choose safer and more effective HIV medication switches, reducing the risk of drug resistance.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test a new drug or cure, and results may not apply to all HIV patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTIRETROVIRAL THERAPY DRUG RESISTANCE, MICROBIAL HIV-1-INFECTION

Contacts and locations

Locations

S.H. Ho Research Centre for Infectious Diseases, The Chinese University of Hong Kong
RECRUITING

Hong Kong, Hong Kong, 0000, China

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