Scientists hunt for smarter treatments for kids with leukemia

NCT ID NCT04478006

Recruiting now Knowledge-focused Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is collecting genetic and drug sensitivity data from 300 children with leukemia to better understand why some cases relapse and how to target them more precisely. Researchers will analyze tumor DNA, gene activity, and test drugs on patient cells in the lab. The goal is to find new, less toxic treatment options for high-risk childhood leukemia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could identify new drug targets and personalized treatment strategies for children with hard-to-treat leukemia.
What could go wrong: This is an observational, translational study, not a treatment trial. Findings may not directly lead to new therapies, and results may take years to impact patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia acute myeloid leukemia childhood leukemia juvenile myelomonocytic leukemia mixed phenotype acute leukemia myelodysplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHILDHOOD LEUKEMIA

Contacts and locations

Locations

Hong Kong Children Hospital
RECRUITING

Hong Kong, Hksar, China

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