Which biopsy method best spots aggressive prostate cancer? major trial launches

NCT ID NCT06303622

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways to guide prostate biopsies using MRI: cognitive-guided (doctor mentally aligns images) and MRI-ultrasound fusion (computer overlays images). It aims to see which method finds more clinically significant prostate cancers. The trial will enroll 1,250 men with suspicious MRI lesions and a PSA under 20.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this trial could show which biopsy method is better at finding aggressive prostate cancers, helping doctors choose the most accurate approach.

What could go wrong

This is a diagnostic comparison study, not a treatment trial. It may not change outcomes directly, and results depend on the skill of the doctors performing the biopsies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong

    Contact Email: •••••@•••••